183904-53-2

183904-53-2 structure

Name: (+)-Dihydrocalanolide A
Chemical Name: (+)-Dihydrocalanolide A
CAS Number: 183904-53-2
Molecular Formula: C₂₂H₂₈O₅
Molecular Weight: 372.45500
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2017-07-06 04:10:50
Modify Date: 2024-01-14 15:18:38
(+)-Dihydrocalanolide A (DHCal A; NSC 678323) is an orally active nonnucleoside inhibitor of Reverse Transcriptase. (+)-Dihydrocalanolide A can be used to HIV infection research[1].

Name	(+)-Dihydrocalanolide A
Synonyms	Dihydrocalanolide A

Description	(+)-Dihydrocalanolide A (DHCal A; NSC 678323) is an orally active nonnucleoside inhibitor of Reverse Transcriptase. (+)-Dihydrocalanolide A can be used to HIV infection research[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Signaling Pathways >> Anti-infection >> Reverse Transcriptase
In Vivo	(+)-Dihydrocalanolide A (25 mg/kg; p.o.; single dose) 具有良好的药代动力学参数，在 CD2F1 小鼠中的口服生物利用度为 64%[1]。
References	[1]. Newman RA, et al. Pharmaceutical properties of related calanolide compounds with activity against human immunodeficiency virus. J Pharm Sci. 1998 Sep;87(9):1077-80.