(+)-Dihydrocalanolide A

Modify Date: 2024-01-14 15:18:38

(+)-Dihydrocalanolide A structure	Common Name	(+)-Dihydrocalanolide A
	CAS Number	183904-53-2	Molecular Weight	372.45500
	Density	1.162g/cm3	Boiling Point	509ºC at 760mmHg
	Molecular Formula	C₂₂H₂₈O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	173.8ºC

Use of (+)-Dihydrocalanolide A

(+)-Dihydrocalanolide A (DHCal A; NSC 678323) is an orally active nonnucleoside inhibitor of Reverse Transcriptase. (+)-Dihydrocalanolide A can be used to HIV infection research[1].

Name	(+)-Dihydrocalanolide A
Synonym	More Synonyms

Description	(+)-Dihydrocalanolide A (DHCal A; NSC 678323) is an orally active nonnucleoside inhibitor of Reverse Transcriptase. (+)-Dihydrocalanolide A can be used to HIV infection research[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Signaling Pathways >> Anti-infection >> Reverse Transcriptase
In Vivo	(+)-Dihydrocalanolide A (25 mg/kg; p.o.; single dose) 具有良好的药代动力学参数，在 CD2F1 小鼠中的口服生物利用度为 64%[1]。
References	[1]. Newman RA, et al. Pharmaceutical properties of related calanolide compounds with activity against human immunodeficiency virus. J Pharm Sci. 1998 Sep;87(9):1077-80.

Density	1.162g/cm3
Boiling Point	509ºC at 760mmHg
Molecular Formula	C₂₂H₂₈O₅
Molecular Weight	372.45500
Flash Point	173.8ºC
Exact Mass	372.19400
PSA	68.90000
LogP	4.29950
Vapour Pressure	3.5E-11mmHg at 25°C
Index of Refraction	1.547

Dihydrocalanolide A