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872679-70-4

872679-70-4 structure
872679-70-4 structure
  • Name: Fmoc-NH-PEG2-CH2CH2COOH
  • Chemical Name: Fmoc-9-Amino-4,7-dioxanonanoic acid
  • CAS Number: 872679-70-4
  • Molecular Formula: C22H25NO6
  • Molecular Weight: 399.437
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
  • Create Date: 2018-11-24 20:17:45
  • Modify Date: 2024-01-03 16:06:11
  • Fmoc-NH-PEG2-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name Fmoc-9-Amino-4,7-dioxanonanoic acid
Synonyms 3-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]propanoic acid
2,7,10-Trioxa-4-azatridecan-13-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-
3-{2-[2-Amino-3-(9H-fluoren-9-ylmethoxy)-3-oxopropoxy]ethoxy}propanoic acid
Serine, O-[2-(2-carboxyethoxy)ethyl]-, 9H-fluoren-9-ylmethyl ester
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10-trioxa-4-azatridecan-13-oic acid
Fmoc-NH-PEG2-CH2CH2COOH
Description Fmoc-NH-PEG2-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Fulcher JM, et al. Chemical synthesis of Shiga toxin subunit B using a next-generation traceless "helping hand" solubilizing tag. Org Biomol Chem. 2019 Dec 28;17(48):10237-10244.

Density 1.3±0.1 g/cm3
Boiling Point 622.1±55.0 °C at 760 mmHg
Molecular Formula C22H25NO6
Molecular Weight 399.437
Flash Point 330.0±31.5 °C
Exact Mass 399.168182
PSA 97.58000
LogP 2.96
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.584
Storage condition -20 ℃
Hazard Codes Xi
HS Code 2932999099
HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%