951671-92-4

951671-92-4 structure

Name: Azido-PEG4-Amine
Chemical Name: 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethanamine
CAS Number: 951671-92-4
Molecular Formula: C₁₀H₂₂N₄O₄
Molecular Weight: 262.30600
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2016-08-02 08:33:27
Modify Date: 2024-01-05 08:16:12
PROTAC Linker 20 is a polyethylene glycol (PEG)-based PROTAC linker. PROTAC Linker 20 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Name	2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethanamine
Synonyms	O-(2-Aminoethyl)-O'-(2-azidoethyl)triethylene Glycol 14-Azido-3,6,9,12-tetraoxatetradecan-1-amine Azido-PEG4-Amine O-(2-Aminoethyl)-O’-(2-azidoethyl)triethylene Glycol

Description	PROTAC Linker 20 is a polyethylene glycol (PEG)-based PROTAC linker. PROTAC Linker 20 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.