59256-52-9
59256-52-9 structure
- Name: Bis-acrylate-PEG5
- Chemical Name: 2-[2-[2-[2-(2-prop-2-enoyloxyethoxy)ethoxy]ethoxy]ethoxy]ethyl prop-2-enoate
- CAS Number: 59256-52-9
- Molecular Formula: C16H26O8
- Molecular Weight: 346.37300
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2016-06-22 20:11:14
- Modify Date: 2024-01-08 14:39:09
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Bis-acrylate-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2-[2-[2-[2-(2-prop-2-enoyloxyethoxy)ethoxy]ethoxy]ethoxy]ethyl prop-2-enoate |
|---|---|
| Synonyms |
EINECS 261-677-8
16-oxo-3,6,9,12,15-pentaoxaoctadec-17-en-1-yl acrylate 3,6,9,12-Tetraoxatetradecane-1,14-diyl diacrylate |
| Description | Bis-acrylate-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.098g/cm3 |
|---|---|
| Boiling Point | 421.5ºC at 760 mmHg |
| Molecular Formula | C16H26O8 |
| Molecular Weight | 346.37300 |
| Flash Point | 181.9ºC |
| Exact Mass | 346.16300 |
| PSA | 89.52000 |
| LogP | 0.51120 |
| Index of Refraction | 1.458 |