623-58-5
623-58-5 structure
- Name: Acetoacetic acid sodium salt
- Chemical Name: sodium,3-oxobutanoate
- CAS Number: 623-58-5
- Molecular Formula: C4H5NaO3
- Molecular Weight: 124.07
- Catalog: Research Areas Metabolic Disease
- Create Date: 2016-10-30 16:26:52
- Modify Date: 2024-01-03 23:13:56
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Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes. Acetoacetic acid sodium salt induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes[1].
| Name | sodium,3-oxobutanoate |
|---|---|
| Synonyms |
Butanoic acid,3-oxo-,sodium salt
sodium acetoacetic acid ester sodium acetoxyacetate sodium 3-oxobutanoate sodium acetylacetonate acetoacetic acid,monosodium salt Sodium Acetoacetate Acetylacetic Acid Sodium salt Acetoacetic acid sodium salt |
| Description | Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes. Acetoacetic acid sodium salt induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Acetoacetic acid sodium salt induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes[1]. Acetoacetic acid (0.6, 2.4, 4.8 mM) increases malondialdehyde (MDA) content in high-dose group (GH) group, decreases mRNA expression of Mn SOD, Cu/Zn SOD, and glutathione peroxidase (GSH-Px) in all groups, lowers catalase (CAT) mRNA expression in medial-dose group (GM), and GH groups. In addition, Acetoacetic acid down-regulates the mRNA expression of apolipoprotein B100 (ApoB100), apolipoprotein E (ApoE), and low density lipoprotein receptor (LDLR). Thus, VLDL assembly is decreased andtriglyceride (TG) accumulation is increased in these bovine hepatocytes[1]. |
| References |
| Boiling Point | 237.7ºC at 760 mmHg |
|---|---|
| Molecular Formula | C4H5NaO3 |
| Molecular Weight | 124.07 |
| Flash Point | 111.8ºC |
| Exact Mass | 124.01400 |
| PSA | 57.20000 |
| HS Code | 2918300090 |
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Detail
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| Literature: Nippon Soda Co., Ltd. Patent: US5484949 A1, 1996 ; |
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623-58-5 |
| Literature: BASF Aktiengesellschaft Patent: US5428174 A1, 1995 ; |
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~77%
623-58-5 |
| Literature: Tommasi, Immacolata; Sorrentino, Fabiana Tetrahedron Letters, 2009 , vol. 50, # 1 p. 104 - 107 |
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623-58-5 |
| Literature: Goemez-Bombarelli, Rafael; Gonzalez-Perez, Marina; Perez-Prior, Maria Teresa; Manso, Jose A.; Calle, Emilio; Casado, Julio Journal of Physical Organic Chemistry, 2009 , vol. 22, # 5 p. 438 - 442 |
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623-58-5 |
| Literature: Franklin, M. C.; Short, W. F. Journal of the Chemical Society, 1928 , p. 591 - 595 |
| HS Code | 2918300090 |
|---|---|
| Summary | 2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |