145672-81-7
145672-81-7 structure
- Name: Cetrorelix Acetate
- Chemical Name: cetrorelix acetate
- CAS Number: 145672-81-7
- Molecular Formula: C72H96ClN17O16
- Molecular Weight: 1491.09000
- Catalog: Peptides
- Create Date: 2017-08-09 02:52:39
- Modify Date: 2024-01-03 12:50:04
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Cetrorelix Acetate is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM. Sequence: N-acetyl-{2-Naph-Ala}-{Cl-Phe}-{3Py-Ala}-Ser-Tyr-{Cit}-Leu-Arg-Pro-Ala-NH2.
| Name | cetrorelix acetate |
|---|
| Description | Cetrorelix Acetate is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM. Sequence: N-acetyl-{2-Naph-Ala}-{Cl-Phe}-{3Py-Ala}-Ser-Tyr-{Cit}-Leu-Arg-Pro-Ala-NH2. |
|---|---|
| Related Catalog | |
| Target |
IC50: 1.21 nM GnRH[1]. |
| In Vitro | Cetrorelix Acetate inhibits growth of ES-2 cell line at 1000 ng/ml. Cetrorelix Acetate has comparable antiproliferative effects as GnRH-I agonists indicating that the dichotomy of GnRH-I agonists and antagonists might not apply to the GnRH-I system in cancer cells[2]. |
| References |
| Molecular Formula | C72H96ClN17O16 |
|---|---|
| Molecular Weight | 1491.09000 |
| Exact Mass | 1489.69000 |
| PSA | 532.97000 |
| LogP | 6.02320 |
| Storage condition | -20°C |
| Symbol |
GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H361 |
| Precautionary Statements | P281 |
| RIDADR | NONH for all modes of transport |