1260075-17-9
1260075-17-9 structure
- Name: Mitapivat
- Chemical Name: N-(4-(4-(cyclopropylmethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide
- CAS Number: 1260075-17-9
- Molecular Formula: C24H26N4O3S
- Molecular Weight: 450.55300
- Catalog: Research Areas Cancer
- Create Date: 2017-05-13 15:36:31
- Modify Date: 2025-08-25 15:41:43
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Mitapivat is a potent human R-type pyruvate kinase (PKR) inhibitor; also shows potency for mutant PKR including R510Q PKR, R532W PKR, T384W PKR etc.
| Name | N-(4-(4-(cyclopropylmethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide |
|---|---|
| Synonyms |
PKM2 activator 1020
Mitapivat |
| Description | Mitapivat is a potent human R-type pyruvate kinase (PKR) inhibitor; also shows potency for mutant PKR including R510Q PKR, R532W PKR, T384W PKR etc. |
|---|---|
| Related Catalog | |
| References |
[1]. PYRUVATE KINASE ACTIVATORS FOR USE IN THERAPY. Patent WO/2012/151451A1 |
| Molecular Formula | C24H26N4O3S |
|---|---|
| Molecular Weight | 450.55300 |
| Exact Mass | 450.17300 |
| PSA | 90.99000 |
| LogP | 4.23300 |