Mitapivat

Modify Date: 2025-08-25 15:41:43

Mitapivat Structure
Mitapivat structure
Common Name Mitapivat
CAS Number 1260075-17-9 Molecular Weight 450.55300
Density N/A Boiling Point N/A
Molecular Formula C24H26N4O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mitapivat


Mitapivat is a potent human R-type pyruvate kinase (PKR) inhibitor; also shows potency for mutant PKR including R510Q PKR, R532W PKR, T384W PKR etc.

 Names

Name N-(4-(4-(cyclopropylmethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide
Synonym More Synonyms

 Mitapivat Biological Activity

Description Mitapivat is a potent human R-type pyruvate kinase (PKR) inhibitor; also shows potency for mutant PKR including R510Q PKR, R532W PKR, T384W PKR etc.
Related Catalog
References

[1]. PYRUVATE KINASE ACTIVATORS FOR USE IN THERAPY. Patent WO/2012/151451A1

 Chemical & Physical Properties

Molecular Formula C24H26N4O3S
Molecular Weight 450.55300
Exact Mass 450.17300
PSA 90.99000
LogP 4.23300

 Synonyms

PKM2 activator 1020
Mitapivat
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