106128-98-7

106128-98-7 structure

Name: MBP (1-11), guinea pig, porcine, rabbit, rat, Myelin Basic Protein (135-145), human,Ac-ASQKRPSQRHG
Chemical Name: MBP (1-11), guinea pig, porcine, rabbit, rat, Myelin Basic Protein (135-145), human,Ac-ASQKRPSQRHG
CAS Number: 106128-98-7
Molecular Formula: C₅₂H₈₈N₂₂O₁₇
Molecular Weight: 1293.39000
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-12-18 12:02:06
Modify Date: 2024-01-08 22:19:38
Myelin Basic Protein (1-11) is an encephalitogenic epitope of myelin basic protein (MBP). Myelin Basic Protein (1-11) can be used for induction of experimental autoimmune encephalomyelitis (EAE)[1][2].

Name	MBP (1-11), guinea pig, porcine, rabbit, rat, Myelin Basic Protein (135-145), human,Ac-ASQKRPSQRHG
Synonyms	myelin basic protein (135-145),human ac-mbp (human,porcine,rat 1-11) acetyl-mbp (135-145) (human) mbp (1-11) human acetyl-myelin a1 protein (135-145) (human) acetyl-myelin basic protein (135-145) (human) ac-asqkrpsqrhg acetyl-golli-mbp1 hog7 (135-145) (human) mbp (1-11),guinea pig,porcine,rabbit,rat acetyl-myelin basic protein (human,rat,1-11) Myelin Basic Protein (135-145)

Description	Myelin Basic Protein (1-11) is an encephalitogenic epitope of myelin basic protein (MBP). Myelin Basic Protein (1-11) can be used for induction of experimental autoimmune encephalomyelitis (EAE)[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vitro	Myelin Basic Protein (1-11) (0-10 μg/mL) 刺激 MBP-TCR CD4 T 细胞产生 IL-2[1]。
In Vivo	Myelin Basic Protein (1-11) (100 μg/mL)-pulsed DC 细胞 (i.p.) 在转移到受照射的 B10.PL 小鼠体内时会诱导实验性自身免疫性脑脊髓炎 (EAE)[1]。 Myelin Basic Protein (1-11) (100 μg，腹腔注射) 诱导成年小鼠对 MBP 的耐受性并预防 MBP 诱导的 EAE[2]。
References	[1]. Dittel BN, et al. Presentation of the self antigen myelin basic protein by dendritic cells leads to experimental autoimmune encephalomyelitis. J Immunol. 1999 Jul 1;163(1):32-9. [2]. Gaur A, et al. Amelioration of autoimmune encephalomyelitis by myelin basic protein synthetic peptide-induced anergy. Science. 1992 Nov 27;258(5087):1491-4.