14365-44-7
14365-44-7 structure
- Name: Adenosine,5'-amino-5'-deoxy
- Chemical Name: 5'-aminoadenosine
- CAS Number: 14365-44-7
- Molecular Formula: C10H14N6O3
- Molecular Weight: 266.26
- Catalog: Biochemical Nucleoside drugs Deoxynucleotides and their analogues
- Create Date: 2018-07-21 17:57:11
- Modify Date: 2026-07-04 14:13:06
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5'-Amino-5'-deoxyadenosine (NH2dAdo; Nsc 238990) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | 5'-aminoadenosine |
|---|---|
| Synonyms |
deoxyadenosinehydrochloride
5'-NH-ADO 5'-AMINOADENOSINE //BP Adenosine, 5'-amino-5'-deoxy- (8ci)(9ci) 5'-AMINOADENOSINE 5'-AMINO-5'-DEOXY-D-ADENOSINE 5'-amino-2',3'-O-isopropylidene-5'-deoxyadenosine Adenosine,5'-aMino-5'-deoxy 5'-amino-5'-deoxyAdo 5’-amino-5’-deoxyadenosine 5''-Amino-5''-deoxyadenosine 5-amino-5-deoxyadenosine 5'-Amino-5'-deoxyadenosine hydrochloride (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(aminomethyl)tetrahydrofuran-3,4-diol 5'-Deoxy-5'-aminoadenosine 5′,-NH2-Ado 5'-Amino-5'-deoxyadenosine Nsc |
| Description | 5'-Amino-5'-deoxyadenosine (NH2dAdo; Nsc 238990) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | |
| References |
| Density | 2.08 g/cm3 |
|---|---|
| Boiling Point | 647.6ºC at 760 mmHg |
| Molecular Formula | C10H14N6O3 |
| Molecular Weight | 266.26 |
| Flash Point | 345.4ºC |
| Exact Mass | 266.11300 |
| PSA | 145.33000 |
| Vapour Pressure | 1.18E-17mmHg at 25°C |
| Index of Refraction | 1.935 |
|
~91%
14365-44-7 |
| Literature: Wang, Ting; Lee, Hyun Joo; Tosh, Dilip K.; Kim, Hea Ok; Pal, Shantanu; Choi, Sun; Lee, Yoonji; Moon, Hyung Ryong; Zhao, Long Xuan; Lee, Kang Man; Jeong, Lak Shin Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 16 p. 4456 - 4459 |
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| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 16 p. 4456 - 4459 |
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| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 16 p. 4456 - 4459 |
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| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 16 p. 4456 - 4459 |
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| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 16 p. 4456 - 4459 |
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| Literature: Journal of Medicinal Chemistry, , vol. 25, # 5 p. 550 - 556 |
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| Literature: Journal of Medicinal Chemistry, , vol. 25, # 5 p. 550 - 556 |
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| Literature: Journal of Medicinal Chemistry, , vol. 25, # 5 p. 550 - 556 |
| Precursor 7 | |
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| DownStream 0 | |