737-76-8

737-76-8 structure

Name: Adenosine,5'-azido-5'-deoxy-
Chemical Name: 2-(6-aminopurin-9-yl)-5-(azidomethyl)oxolane-3,4-diol
CAS Number: 737-76-8
Molecular Formula: C₁₀H₁₂N₈O₃
Molecular Weight: 292.25
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2016-01-21 06:18:05
Modify Date: 2024-02-19 13:06:03
5′-Azido-5′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2-(6-aminopurin-9-yl)-5-(azidomethyl)oxolane-3,4-diol
Synonyms	5'-Azido-5'-desoxy-adenosin 5'-azido-5'-deoxyAdo 5'-Deoxy-5'-azido-adenosin 5'-Deoxy-5'-azidoadenosine 5'-Azidoadenosine 5'-azido-5'-deoxyadenosine

Description	5′-Azido-5′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.