1043-21-6

1043-21-6 structure

Name: Pirenoxine
Chemical Name: 1,5-dioxo-4H-pyrido[3,2-a]phenoxazine-3-carboxylic acid
CAS Number: 1043-21-6
Molecular Formula: C₁₆H₈N₂O₅
Molecular Weight: 308.25
Catalog: API Special medicine Ophthalmic medication
Create Date: 2018-03-09 08:00:00
Modify Date: 2026-07-04 11:28:03
Pirenoxine (Catalin K) is a potent antioxidant. Pirenoxine shows anti-presbyopic activity. Pirenoxine has the potential for the research of cataracts[1][2].

Name	1,5-dioxo-4H-pyrido[3,2-a]phenoxazine-3-carboxylic acid
Synonyms	1-hydroxy-5-oxo-5h-pyrido[3,2-a]phenoxazine-3-cboxylic acid 1-hydroxy-5-oxo-5H-pyrido[3,2-a]-phenoxazine-3-carboxylic acid Pirenoxina [Spanish] 1,5-dioxo-1,5-dihydro-4H-pyrido[3,2-a]phenoxazine-3-carboxylic acid pirenoxine Pirenoxinum Catalin K Ky Uni EINECS 213-872-4 5H-Pyrido[3,2-a]phenoxazine-3-cboxylic acid, 1-hydroxy-5-oxo 1-Hydroxy-5-oxo-5H-pyrido[3,2-]phenoxazine-3-cboxylicacid Pirenoxinum [Latin] Catalin Catalin-K (TN) PIRENOXINE Pirenoxina Pirenoxine //BP 1,5-dioxo-4H-pyrido[3,2-a]phenoxazine-3-cboxylic acid 1-Hydroxy-5H-pyrido[3,2-a]phenoxazin-5-one-3-cboxylic acid 1,5-dioxo-4,5-dihydro-1H-pyrido[3,2-a]phenoxazine-3-cboxylic acid 1-Hydroxy-pyrido-5-phenoxazon-3-carbonsaeure Bernetine 1-Hydroxy-3-cboxy-5H-pyrido[3,2-a]phenoxazin-5-one MFCD00867148 catalin pirfenoxone

Description	Pirenoxine (Catalin K) is a potent antioxidant. Pirenoxine shows anti-presbyopic activity. Pirenoxine has the potential for the research of cataracts[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vivo	Pirenoxine (0.005% pirenoxine；滴眼液) 抑制晶状体硬化并防止老花眼的发展[2]。 Animal Model: Six-week-old male Sprague-Dawley rats[2] Dosage: 0.005% pirenoxine Administration: Eye drop Result: Significantly suppressed lens hardening.
References	[1]. Upaphong P, et al. The Possible Positive Mechanisms of Pirenoxine in Cataract Formation. Int J Mol Sci. 2022 Aug 21;23(16):9431. [2]. Tsuneyoshi Y, et al. Suppression of presbyopia progression with pirenoxine eye drops: experiments on rats and non-blinded, randomized clinical trial of efficacy. Sci Rep. 2017 Jul 28;7(1):6819.