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  • DC Chemicals Limited
  • China
  • Product Name: PRX
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

1043-21-6

1043-21-6 structure
1043-21-6 structure
  • Name: Pirenoxine
  • Chemical Name: 1,5-dioxo-4H-pyrido[3,2-a]phenoxazine-3-carboxylic acid
  • CAS Number: 1043-21-6
  • Molecular Formula: C16H8N2O5
  • Molecular Weight: 308.25
  • Catalog: API Special medicine Ophthalmic medication
  • Create Date: 2018-03-09 08:00:00
  • Modify Date: 2024-01-03 12:51:29
  • Pirenoxine (Catalin K) is a potent antioxidant. Pirenoxine shows anti-presbyopic activity. Pirenoxine has the potential for the research of cataracts[1][2].

Name 1,5-dioxo-4H-pyrido[3,2-a]phenoxazine-3-carboxylic acid
Synonyms 1-hydroxy-5-oxo-5H-pyrido[3,2-a]-phenoxazine-3-carboxylic acid
Pirenoxina [Spanish]
1,5-dioxo-1,5-dihydro-4H-pyrido[3,2-a]phenoxazine-3-carboxylic acid
pirenoxine
Pirenoxinum
EINECS 213-872-4
1-Hydroxy-pyrido-5-phenoxazon-3-carbonsaeure
Pirenoxinum [Latin]
Catalin
Catalin-K (TN)
MFCD00867148
Pirenoxina
pirfenoxone
Description Pirenoxine (Catalin K) is a potent antioxidant. Pirenoxine shows anti-presbyopic activity. Pirenoxine has the potential for the research of cataracts[1][2].
Related Catalog
In Vivo Pirenoxine (0.005% pirenoxine;滴眼液) 抑制晶状体硬化并防止老花眼的发展[2]。 Animal Model: Six-week-old male Sprague-Dawley rats[2] Dosage: 0.005% pirenoxine Administration: Eye drop Result: Significantly suppressed lens hardening.
References

[1]. Upaphong P, et al. The Possible Positive Mechanisms of Pirenoxine in Cataract Formation. Int J Mol Sci. 2022 Aug 21;23(16):9431.  

[2]. Tsuneyoshi Y, et al. Suppression of presbyopia progression with pirenoxine eye drops: experiments on rats and non-blinded, randomized clinical trial of efficacy. Sci Rep. 2017 Jul 28;7(1):6819.  

Density 1.7g/cm3
Boiling Point 515.8ºC at 760mmHg
Melting Point 247-248ºC
Molecular Formula C16H8N2O5
Molecular Weight 308.25
Flash Point 265.7ºC
Exact Mass 308.04300
PSA 113.52000
LogP 2.24480
Vapour Pressure 1.83E-11mmHg at 25°C
Index of Refraction 1.793