1158-10-7

1158-10-7 structure

Name: 3,5-Diiodothyropropionic Acid
Chemical Name: 3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]propanoic acid
CAS Number: 1158-10-7
Molecular Formula: C₁₅H₁₂I₂O₄
Molecular Weight: 510.06200
Catalog: Research Areas Cardiovascular Disease
Create Date: 2017-10-07 10:05:19
Modify Date: 2024-01-21 15:42:00
3,5-Diiodothyropropionic acid is a thyroid hormone analog, induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (TR), with Ka of 2.40 and 4.06 M-1 for TRα1 and TRβ1, respectively[1].

Name	3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]propanoic acid
Synonyms	DITPA 3-[4-(4-hydroxy-phenoxy)-3,5-diiodo-phenyl]-propionic acid 3,5-Ditpa Dipro DIPTA 3-[4-(4-Hydroxy-phenoxy)-3,5-dijod-phenyl]-propionsaeure MFCD00045945 3-<4-(4-Hydroxy-phenoxy)-3,5-diiod-phenyl>-propionsaeure 3,5-Diiod-thyropropionsaeure 3,5-DIIODO-4-(4-HYDROXYPHENOXY)HYDROCINNAMIC ACID 3,5-Diiodothyropropionic acid

Description	3,5-Diiodothyropropionic acid is a thyroid hormone analog, induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (TR), with Ka of 2.40 and 4.06 M-1 for TRα1 and TRβ1, respectively[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Thyroid Hormone Receptor
References	[1]. Pennock GD, et al. Cardiac effects of 3,5-diiodothyropropionic acid, a thyroid hormone analog with inotropic selectivity. J Pharmacol Exp Ther. 1992 Oct;263(1):163-9.

HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%