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1824-58-4

1824-58-4 structure

1824-58-4 structure

Name: 6-chloro-3-ethyl-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide
Chemical Name: 6-chloro-3-ethyl-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide
CAS Number: 1824-58-4
Molecular Formula: C₉H₁₂ClN₃O₄S₂
Molecular Weight: 325.79200
Create Date: 2018-05-23 08:00:00
Modify Date: 2026-06-30 21:46:45

Name	6-chloro-3-ethyl-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide
Synonyms	Eclotizide 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-ethyl-3,4-dihydro-, 1,1-dioxide Eclotizidum Ethiazide [INN:BAN:JAN] 6-chloro-3-ethyl-1,1-dioxo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide ETHIAZIDE 3-Ethylhydrochlorothiazide aethiazidum Etizide Neo-diuresal Etiazide [DCIT] ethiazide 6-chloro-3-ethyl-1,1-diketo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 6-Chloro-3-ethyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide 6-Chlor-7-sulfamoyl-3-aethyl-3,4-dihydro-1,2,4-benzothiadiazin-1,1-dioxid Salta Ethiazidum [INN-Latin] 6-Chlor-7-sulfamoyl-3-aethyl-1,1-dioxy-3,4-dihydro-2H-1,2,4-benzothiadiazin Aethiazidum 6-Chlor-3-aethyl-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazin-1,1-dioxid Etiazida [INN-Spanish] 6-Chlor-3-aethyl-1,1-dioxy-7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazin Neo Diuresal

Density	1.526g/cm3
Boiling Point	563.5ºC at 760mmHg
Molecular Formula	C₉H₁₂ClN₃O₄S₂
Molecular Weight	325.79200
Flash Point	294.6ºC
Exact Mass	324.99600
PSA	135.12000
LogP	3.75600
Vapour Pressure	1.01E-12mmHg at 25°C
Index of Refraction	1.589

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DK9460000

CHEMICAL NAME :: 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-ethyl-3,4-dihydro-, 1,1-dioxide

CAS REGISTRY NUMBER :: 1824-58-4

LAST UPDATED :: 199109

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C9-H12-Cl-N3-O4-S2

MOLECULAR WEIGHT :: 325.81

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,775,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,110,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,110,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,775,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,775,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,775,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >310 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,775,1979

HS Code	2935009090

Precursor 0
DownStream 2
121-30-2 1824-58-4

HS Code	2935009090
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

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