16526-56-0
16526-56-0 structure
- Name: Adenosine, 2-methyl-
- Chemical Name: 2-methyladenosine
- CAS Number: 16526-56-0
- Molecular Formula: C11H15N5O4
- Molecular Weight: 281.27
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2016-09-12 18:37:43
- Modify Date: 2024-01-07 04:35:31
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2-Methyladenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
| Name | 2-methyladenosine |
|---|---|
| Synonyms |
2-methyl-adenosine
2-Methyladenosine 2-Methyl-adenosin 2-C-methyladenosine |
| Description | 2-Methyladenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.96g/cm3 |
|---|---|
| Boiling Point | 517.8ºC at 760mmHg |
| Molecular Formula | C11H15N5O4 |
| Molecular Weight | 281.27 |
| Flash Point | 266.9ºC |
| Exact Mass | 281.11200 |
| PSA | 139.54000 |
| Vapour Pressure | 1.51E-11mmHg at 25°C |
| Index of Refraction | 1.856 |
|
~%
16526-56-0 |
| Literature: GENZYME CORPORATION Patent: WO2008/157438 A1, 2008 ; Location in patent: Page/Page column 29-30 ; |
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~37%
16526-56-0 |
| Literature: Nippon Zoki Pharmaceutical Co., Ltd. Patent: US4843066 A1, 1989 ; |
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~%
16526-56-0 |
| Literature: Hirth, Bradford; Barker Jr., Robert H.; Celatka, Cassandra A.; Klinger, Jeffrey D.; Liu, Hanlan; Nare, Bakela; Nijjar, Amarjit; Phillips, Margaret A.; Sybertz, Edmund; Willert, Erin K.; Xiang, Yibin Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 11 p. 2916 - 2919 |
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~%
16526-56-0 |
| Literature: Davoll; Lowy Journal of the American Chemical Society, 1952 , vol. 74, p. 1563,1565 |
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~%
16526-56-0
Detail
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| Literature: Zady, Mona F.; Wong, John L. Journal of Organic Chemistry, 1980 , vol. 45, # 12 p. 2373 - 2377 |
| Precursor 7 | |
|---|---|
| DownStream 0 | |