26383-05-1

26383-05-1 structure
26383-05-1 structure
  • Name: Adenosine,3'-deoxy-3'-methyl-
  • Chemical Name: 2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-4-methyloxolan-3-ol
  • CAS Number: 26383-05-1
  • Molecular Formula: C11H15N5O3
  • Molecular Weight: 265.27
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2017-07-18 08:39:31
  • Modify Date: 2024-01-02 14:13:24
  • 3’-Deoxy-3’-α-C-methyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name 2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-4-methyloxolan-3-ol
Synonyms 3'-methyl-3'-deoxy-adenosine
5-cyanomethyl-3-cyclohexyl-3-methyl-oxazolidinium,chloride
3-Methyl-3-cyclohexyl-5-cyanmethyl-oxazolidinium chlorid
Description 3’-Deoxy-3’-α-C-methyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Density 1.81g/cm3
Boiling Point 606.4ºC at 760 mmHg
Molecular Formula C11H15N5O3
Molecular Weight 265.27
Flash Point 320.5ºC
Exact Mass 265.11700
PSA 119.31000
Vapour Pressure 1.48E-15mmHg at 25°C
Index of Refraction 1.818

~77%

26383-05-1 structure

26383-05-1

Literature: Aljarah, Mohamed; Couturier, Sarah; Gosselin, Gilles; Mathe, Christophe; Perigaud, Christian Nucleosides, Nucleotides and Nucleic Acids, 2007 , vol. 26, # 8-9 p. 1125 - 1128