Adenosine,3'-deoxy-3'-methyl-

Modify Date: 2024-01-02 14:13:24

Adenosine,3'-deoxy-3'-methyl- Structure
Adenosine,3'-deoxy-3'-methyl- structure
Common Name Adenosine,3'-deoxy-3'-methyl-
CAS Number 26383-05-1 Molecular Weight 265.27
Density 1.81g/cm3 Boiling Point 606.4ºC at 760 mmHg
Molecular Formula C11H15N5O3 Melting Point N/A
MSDS N/A Flash Point 320.5ºC

 Use of Adenosine,3'-deoxy-3'-methyl-


3’-Deoxy-3’-α-C-methyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-4-methyloxolan-3-ol
Synonym More Synonyms

 Adenosine,3'-deoxy-3'-methyl- Biological Activity

Description 3’-Deoxy-3’-α-C-methyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.81g/cm3
Boiling Point 606.4ºC at 760 mmHg
Molecular Formula C11H15N5O3
Molecular Weight 265.27
Flash Point 320.5ºC
Exact Mass 265.11700
PSA 119.31000
Vapour Pressure 1.48E-15mmHg at 25°C
Index of Refraction 1.818

 Synthetic Route

~77%

Adenosine,3'-deoxy-3'-methyl- Structure

Adenosine,3'-de...

CAS#:26383-05-1

Literature: Aljarah, Mohamed; Couturier, Sarah; Gosselin, Gilles; Mathe, Christophe; Perigaud, Christian Nucleosides, Nucleotides and Nucleic Acids, 2007 , vol. 26, # 8-9 p. 1125 - 1128

 Synonyms

3'-methyl-3'-deoxy-adenosine
5-cyanomethyl-3-cyclohexyl-3-methyl-oxazolidinium,chloride
3-Methyl-3-cyclohexyl-5-cyanmethyl-oxazolidinium chlorid