Name | 2-Cyanoethyl N,N-diisopropylchlorophosphoramidite |
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Synonyms |
Phosphoramidochloridous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl ester
2-CYANOETHYL N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE 2-cyanoethyl dipropan-2-ylphosphoramidochloridoite 2-Cyanoethyldiisopropylchlorophosphoramidite 2-Cyanoethyl diisopropylphosphoramidochloridoite 2-Cyanoethyl diisopropylamidochlorophosphite MFCD00011544 3-[chloro-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile |
Density | 1.061 g/mL at 25 °C(lit.) |
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Boiling Point | 343.8±0.0 °C at 760 mmHg |
Molecular Formula | C9H18ClN2OP |
Molecular Weight | 236.679 |
Flash Point | 135.8±28.4 °C |
Exact Mass | 236.084534 |
PSA | 49.85000 |
LogP | 3.46 |
Vapour Pressure | 0.0±0.7 mmHg at 25°C |
Index of Refraction | n20/D 1.479 |
Storage condition | −20°C |
Synonym:Chloro(diisopropylamino)--cyanoethoxyphosphin Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 20/21/22 29 34 5 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Harmful by inhalation, in contact with skin and if swallowed. Contact with water liberates toxic gas. Causes burns. Heating may cause an explosion. Potential Health Effects Eye: Causes eye burns. Skin: Harmful if absorbed through the skin. Causes skin burns. Ingestion: Harmful if swallowed. Causes gastrointestinal tract burns. Inhalation: Harmful if inhaled. Causes chemical burns to the respiratory tract. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Do not induce vomiting. Get medical aid immediately. Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water Reactive. Material will react with water and may release a flammable and/or toxic gas. May explode when heated. Extinguishing Media: Use foam, dry chemical, or carbon dioxide. DO NOT USE WATER! Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Use a spark-proof tool. Section 7 - HANDLING and STORAGE Handling: Use spark-proof tools and explosion proof equipment. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood. Storage: Store in a tightly closed container. Store in a dry area. Corrosives area. Deep freeze (below -20C). Store under nitrogen. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels. Exposure Limits CAS# 89992-70-1: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Liquid Color: Not available. Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: Not available. Autoignition Temperature: Not available. Flash Point: 110 deg C ( 230.00 deg F) Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: 1.061 Molecular Formula: C9H18ClN2OP Molecular Weight: 236.68 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Heating may cause an explosion. Moisture sensitive. Conditions to Avoid: Incompatible materials, exposure to moist air or water, heat. Incompatibilities with Other Materials: Strong oxidizing agents, strong bases, alcohols. Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon monoxide, oxides of phosphorus, carbon dioxide. Hazardous Polymerization: Will not occur. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 89992-70-1 unlisted. LD50/LC50: Not available. Carcinogenicity: 2-Cyanoethyl N,N-diisopropylchlorophosphoramidite - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.* Hazard Class: 8 UN Number: 3265 Packing Group: II IMO Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S. Hazard Class: 8 UN Number: 3265 Packing Group: II RID/ADR Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S. Hazard Class: 8 UN Number: 3265 Packing group: II Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: C Risk Phrases: R 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. R 29 Contact with water liberates toxic gas. R 34 Causes burns. R 5 Heating may cause an explosion. Safety Phrases: S 8 Keep container dry. S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 89992-70-1: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 89992-70-1 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 89992-70-1 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
Symbol |
GHS02, GHS05 |
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Signal Word | Danger |
Hazard Statements | H250-H314 |
Precautionary Statements | P222-P231-P280-P305 + P351 + P338-P310-P422 |
Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
Hazard Codes | C:Corrosive; |
Risk Phrases | R20/21/22;R29;R34;R5 |
Safety Phrases | S26-S36/37/39-S45-S8 |
RIDADR | UN 2845 4.2/PG 1 |
WGK Germany | 3 |
Packaging Group | II |
Hazard Class | 8 |