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Product Name: Temgicoluril
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ShangHai DC Chemicals Co.,Ltd
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Product Name: Temgicoluril
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10095-06-4

10095-06-4 structure

10095-06-4 structure

Name: Temgicoluril
Chemical Name: 1,3,4,6-tetramethyl-3a,6a-dihydroimidazo[4,5-d]imidazole-2,5-dione
CAS Number: 10095-06-4
Molecular Formula: C₈H₁₄N₄O₂
Molecular Weight: 198.22
Catalog: Signaling Pathways Membrane Transporter/Ion Channel GABA Receptor
Create Date: 2016-01-31 10:29:47
Modify Date: 2024-01-06 23:57:03
Tetramethylglycerol (Tetramethylglycoluril) is a small molecule that acts on GABA Receptor, with anti-anxiety activity[1].

Name	1,3,4,6-tetramethyl-3a,6a-dihydroimidazo[4,5-d]imidazole-2,5-dione
Synonyms	mebikar 2,4,6,8-Tetramethyl-2,4,6,8-tetraazobicyclo(3.3.0)octane-3,7-dione Imidazo(4,5-d)imidazole-2,5(1H,3H)-dione,tetrahydro-1,3,4,6-tetramethyl Mebicar 2,4,6,8-Tetramethyl-2,4,6,8-tetraazobizykl(3,3,0)oktandion-3,7 [German] 2,4,6,8-Tetraazabicyclo[3.3.0]octane-3,7-dione,2,4,6,8-tetramethyl Tetrahydro-1,3,4,6-tetramethylimidazo(4,5-d)imidazole-2,5(1H,3H)-dione (2,4,6,8-tetramethyl-2,4,6,8-tetraazabicyclo[3.3.0]octane-3,7-dione) 2,4,6,8-tetramethylglycoluril 1,3,4,6-tetramethyltetrahydroimidazo[4,5-d]imidazole-2,5(1H,3H)-dione Temgicoluril

Description	Tetramethylglycerol (Tetramethylglycoluril) is a small molecule that acts on GABA Receptor, with anti-anxiety activity[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
References	[1]. Val'dman AV, Zaikonnikova IV, Kozlovskaia MM, Zimakova IE. Izuchenie osobennosteĭ spektra psikhotropnogo deĭstviia mebikara [Characteristics of the psychotropic spectrum of action of mebicar]. Biull Eksp Biol Med. 1980 May;89(5):568-70. Russian.

Density	1.237g/cm3
Boiling Point	362.2ºC at 760 mmHg
Molecular Formula	C₈H₁₄N₄O₂
Molecular Weight	198.22
Flash Point	171.9ºC
Exact Mass	198.11200
PSA	47.10000
Vapour Pressure	1.96E-05mmHg at 25°C
Index of Refraction	1.534

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NI2938600

CHEMICAL NAME :: Imidazo(4,5-d)imidazole-2,5(1H,3H)-dione, tetrahydro-1,3,4,6-tetramethyl-

CAS REGISTRY NUMBER :: 10095-06-4

LAST UPDATED :: 198910

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C8-H14-N4-O2

MOLECULAR WEIGHT :: 198.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3450 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GWXXBX German Offenlegungsschrift Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #3306128

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GWXXBX German Offenlegungsschrift Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #3306128

Hazard Codes	Xi
HS Code	2933990090

263403-90-3 structure

263403-90-3

~%

10095-06-4 structure

10095-06-4

Literature: Chemistry of Heterocyclic Compounds, , vol. 38, # 10 p. 1250 - 1252

131543-46-9 structure

131543-46-9

598-94-7 structure

598-94-7

~%

10095-06-4 structure

10095-06-4

Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 7, p. 238

Precursor 2
263403-90-3 598-94-7
DownStream 0

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%