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  • Product Name: Dextramycine
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  • Purity: 98.0%
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134-90-7

134-90-7 structure
134-90-7 structure
  • Name: Dextramycine
  • Chemical Name: [S-(R*,R*)]-2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
  • CAS Number: 134-90-7
  • Molecular Formula: C11H12Cl2N2O5
  • Molecular Weight: 323.13
  • Catalog: Research Areas Infection
  • Create Date: 2017-12-25 15:56:12
  • Modify Date: 2024-01-02 07:59:01
  • L-(+)-threo-Chloramphenicol ((+)-Chloramphenicol) is the S,S-stereoisomer of Chloramphenicol (HY-B0239). L-(+)-Threo-chloramphenicol inhibits protein synthesis in reticulocytes. L-(+)-threo-Chloramphenicol also inhibits the oxidative activity of isolated mitochondria[1][2].

Name [S-(R*,R*)]-2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
Synonyms EINECS 205-161-2
Description L-(+)-threo-Chloramphenicol ((+)-Chloramphenicol) is the S,S-stereoisomer of Chloramphenicol (HY-B0239). L-(+)-Threo-chloramphenicol inhibits protein synthesis in reticulocytes. L-(+)-threo-Chloramphenicol also inhibits the oxidative activity of isolated mitochondria[1][2].
Related Catalog
References

[1]. 3rd WG, et, al. The effect of chloramphenicol in intact erythroid cells. J Mol Biol. 1966 Nov 28;21(3):537-53.  

[2]. Gordon PA, et, al. Effects of chloramphenicol isomers and erythromycin on enzyme and lipid synthesis induced by oxygen in wild-type and petite yeast. J Bacteriol. 1972 May;110(2):504-10.  

Density 1.547g/cm3
Boiling Point 644.9ºC at 760 mmHg
Molecular Formula C11H12Cl2N2O5
Molecular Weight 323.13
Flash Point 343.8ºC
Exact Mass 322.01200
PSA 115.38000
LogP 1.82310
Vapour Pressure 1.63E-17mmHg at 25°C
Index of Refraction 1.611

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AB6835000
CHEMICAL NAME :
Acetamide, 2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p- nitrophenethyl)-, L-threo-(+)-
CAS REGISTRY NUMBER :
134-90-7
LAST UPDATED :
199410
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C11-H12-Cl2-N2-O5
MOLECULAR WEIGHT :
323.15

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
500 umol/L
REFERENCE :
BBRCA9 Biochemical and Biophysical Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 78,151,1977
HS Code 2924299090
Precursor  0

DownStream  2

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%