Dextramycine

Modify Date: 2024-01-02 07:59:01

Dextramycine structure	Common Name	Dextramycine
	CAS Number	134-90-7	Molecular Weight	323.13
	Density	1.547g/cm3	Boiling Point	644.9ºC at 760 mmHg
	Molecular Formula	C₁₁H₁₂Cl₂N₂O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	343.8ºC

Use of Dextramycine

L-(+)-threo-Chloramphenicol ((+)-Chloramphenicol) is the S,S-stereoisomer of Chloramphenicol (HY-B0239). L-(+)-Threo-chloramphenicol inhibits protein synthesis in reticulocytes. L-(+)-threo-Chloramphenicol also inhibits the oxidative activity of isolated mitochondria[1][2].

Name	[S-(R,R)]-2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
Synonym	More Synonyms

Description	L-(+)-threo-Chloramphenicol ((+)-Chloramphenicol) is the S,S-stereoisomer of Chloramphenicol (HY-B0239). L-(+)-Threo-chloramphenicol inhibits protein synthesis in reticulocytes. L-(+)-threo-Chloramphenicol also inhibits the oxidative activity of isolated mitochondria[1][2].
Related Catalog	Research Areas >> Infection
References	[1]. 3rd WG, et, al. The effect of chloramphenicol in intact erythroid cells. J Mol Biol. 1966 Nov 28;21(3):537-53. [2]. Gordon PA, et, al. Effects of chloramphenicol isomers and erythromycin on enzyme and lipid synthesis induced by oxygen in wild-type and petite yeast. J Bacteriol. 1972 May;110(2):504-10.

Description

Related Catalog

Research Areas >> Infection

References

[1]. 3rd WG, et, al. The effect of chloramphenicol in intact erythroid cells. J Mol Biol. 1966 Nov 28;21(3):537-53.

[2]. Gordon PA, et, al. Effects of chloramphenicol isomers and erythromycin on enzyme and lipid synthesis induced by oxygen in wild-type and petite yeast. J Bacteriol. 1972 May;110(2):504-10.

Density	1.547g/cm3
Boiling Point	644.9ºC at 760 mmHg
Molecular Formula	C₁₁H₁₂Cl₂N₂O₅
Molecular Weight	323.13
Flash Point	343.8ºC
Exact Mass	322.01200
PSA	115.38000
LogP	1.82310
Vapour Pressure	1.63E-17mmHg at 25°C
Index of Refraction	1.611

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AB6835000

CHEMICAL NAME :: Acetamide, 2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p- nitrophenethyl)-, L-threo-(+)-

CAS REGISTRY NUMBER :: 134-90-7

LAST UPDATED :: 199410

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C11-H12-Cl2-N2-O5

MOLECULAR WEIGHT :: 323.15

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Bacteria - Escherichia coli

DOSE/DURATION :: 500 umol/L

REFERENCE :: BBRCA9 Biochemical and Biophysical Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 78,151,1977

HS Code	2924299090

Precursor 0
DownStream 2
CAS#:26367-75-9 dehydrochloramp... CAS#:6158-95-8 4-[(3-bromo-4-m...

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

EINECS 205-161-2

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Dextramycine

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Dextramycine Biological Activity

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