317846-22-3

317846-22-3 structure

Name: JNJ-2408068
Chemical Name: 2-[[2-[[1-(2-aminoethyl)piperidin-4-yl]amino]-4-methylbenzimidazol-1-yl]methyl]-6-methylpyridin-3-ol
CAS Number: 317846-22-3
Molecular Formula: C₂₂H₃₀N₆O
Molecular Weight: 394.51300
Catalog: Signaling Pathways Anti-infection RSV
Create Date: 2017-02-07 20:18:49
Modify Date: 2024-01-27 10:47:33
JNJ 2408068 is a potent RSV (respiratory syncytial virus) inhibitor. JNJ 2408068 significantly inhibits replication of RSV A and B subtypes in the lungs of cotton rats without any evidence of toxicity. The minimum protective dose of JNJ 2408068 appears to be approximately 0.39 mg/kg[1].

Name	2-[[2-[[1-(2-aminoethyl)piperidin-4-yl]amino]-4-methylbenzimidazol-1-yl]methyl]-6-methylpyridin-3-ol
Synonyms	unii-ab821dl88a

Description	JNJ 2408068 is a potent RSV (respiratory syncytial virus) inhibitor. JNJ 2408068 significantly inhibits replication of RSV A and B subtypes in the lungs of cotton rats without any evidence of toxicity. The minimum protective dose of JNJ 2408068 appears to be approximately 0.39 mg/kg[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> RSV
Target	RSV-A RSV-B
References	[1]. Wyde PR, et al. Short duration aerosols of JNJ 2408068 (R170591) administered prophylactically or therapeutically protect cotton rats from experimental respiratory syncytial virus infection. Antiviral Res. 2003 Nov;60(3):221-31.