1019640-33-5

1019640-33-5 structure

Name: Sitamaquine tosylate
Chemical Name: N,N-Diethyl-N'-(6-methoxy-4-methyl-8-quinolinyl)-1,6-hexanediamin e 4-methylbenzenesulfonate (1:1)
CAS Number: 1019640-33-5
Molecular Formula: C₂₈H₄₁N₃O₄S
Molecular Weight: 515.70800
Catalog: Research Areas Infection
Create Date: 2016-03-10 12:16:29
Modify Date: 2024-01-07 09:24:36
Sitamaquine (WR 6026) tosylate, an orally active 8-aminoquinoline analog, is an antileishmanial agent. Sitamaquine is a lipophilic weak base that rapidly accumulates in acidic compartments of Leishmania spp., mainly in acidocalcisomes[1].

Name	N,N-Diethyl-N'-(6-methoxy-4-methyl-8-quinolinyl)-1,6-hexanediamin e 4-methylbenzenesulfonate (1:1)
Synonyms	Sitagliptin phosphate hydrate (2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine dihydrogenphosphate monohydrate Sitagliptin phosphate hydrate (jan) Sitagliptin monohydrate sitamaquine tosylate 3(R)-3-amino-1-[3-(trifluoromethyl)-5H,6H,7H,8H [1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one phosphate monohydrate Sitagliptin phosphate (usan) N,N-diethyl-N'-[4-methyl-6-(methyloxy)-8-quinolinyl]-1,6-hexanediamine tosylate Januvia (tn) Sitagliptin phosphate for research 7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)Butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazinephosphatemonohydrate

Description	Sitamaquine (WR 6026) tosylate, an orally active 8-aminoquinoline analog, is an antileishmanial agent. Sitamaquine is a lipophilic weak base that rapidly accumulates in acidic compartments of Leishmania spp., mainly in acidocalcisomes[1].
Related Catalog	Research Areas >> Infection
References	[1]. López-Martín C, et al. Sitamaquine sensitivity in Leishmania species is not mediated by drug accumulation in acidocalcisomes. Antimicrob Agents Chemother. 2008;52(11):4030-4036.

RIDADR	NONH for all modes of transport