163120-31-8

163120-31-8 structure

Name: BYK 49187
Chemical Name: 2-[4-(4-Methyl-1H-imidazol-5-yl)-1-piperidinyl]-4,5-dihydro-6H-im idazo[4,5,1-ij]quinolin-6-one
CAS Number: 163120-31-8
Molecular Formula: C₁₉H₂₁N₅O
Molecular Weight: 335.40
Catalog: Signaling Pathways Cell Cycle/DNA Damage PARP
Create Date: 2016-11-05 01:33:13
Modify Date: 2024-02-25 20:04:39
AR-C66096 (FPL 66096) tetrasodium is a selective platelet P2YT receptor antagonist. AR-C66096 tetrasodium effectively blocks ADP-induced platelet aggregation. AR-C66096 tetrasodium can be used in the research of thromboembolism[1].

Name	2-[4-(4-Methyl-1H-imidazol-5-yl)-1-piperidinyl]-4,5-dihydro-6H-im idazo[4,5,1-ij]quinolin-6-one

Description	AR-C66096 (FPL 66096) tetrasodium is a selective platelet P2YT receptor antagonist. AR-C66096 tetrasodium effectively blocks ADP-induced platelet aggregation. AR-C66096 tetrasodium can be used in the research of thromboembolism[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> PARP Signaling Pathways >> Cell Cycle/DNA Damage >> PARP
Target	pIC50: 8.36 (hPARP-1); 7.50 (mPARP-2)[1].
References	[1]. Eltze T, et al. Imidazoquinolinone, imidazopyridine, and isoquinolindione derivatives as novel and potent inhibitors of the poly(ADP-ribose) polymerase (PARP): a comparison with standard PARP inhibitors. Mol Pharmacol. 2008 Dec;74(6):1587-98.