1227-61-8

1227-61-8 structure
1227-61-8 structure

Name N-[2-(diethylamino)ethyl]-2-(4-methoxyphenoxy)acetamide,hydrochloride
Synonyms p-Methoxyphenoxyacetic acid 2-(diethylamino)ethylamide
p-Methoxyphenoxyacetic acid 2-[diethylamino]ethylamide
Mefexamide hydrochloride
4-Methoxy-phenoxyessigsaeure-<2-diethylamino-ethylamid>
N,N-Diethyl-N'-<(4-methoxy-phenoxy)-acetyl>-ethylendiamin
mefexamide
Description Mefexamide is a particular psychostimulant.
Related Catalog
Density 1.0586 (rough estimate)
Boiling Point 460.4ºC at 760 mmHg
Molecular Formula C15H24N2O3
Molecular Weight 280.36
Flash Point 232.2ºC
PSA 50.80000
LogP 2.72490
Vapour Pressure 1.17E-08mmHg at 25°C
Index of Refraction 1.5800 (estimate)
Storage condition 2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AB7175000
CHEMICAL NAME :
Acetamide, N-(2-(diethylamino)ethyl)-2-(p-methoxyphenoxy)-
CAS REGISTRY NUMBER :
1227-61-8
LAST UPDATED :
199712
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C15-H24-N2-O3
MOLECULAR WEIGHT :
280.41
WISWESSER LINE NOTATION :
2N2&2MV1OR DO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 1,444,1966
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
110 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMXXAJ French Medicament Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Discontinued. Volume(issue)/page/year: #2702M
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
135 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AMPYAT Annales Medico-Psychologiques. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1-Series 11, V.2, 1843-1921; V.80- 1922- Volume(issue)/page/year: 123,141,1965
Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H300-H310-H330
Precautionary Statements P260-P264-P280-P284-P302 + P350-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes T+
Risk Phrases 26/27/28
Safety Phrases 22-36/37/39-45
RIDADR UN 2811 6.1/PG 1
WGK Germany 3
RTECS AB7175000
HS Code 2924299090

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1227-61-8 structure

1227-61-8

Literature: Journal fuer Praktische Chemie (Leipzig), , vol. 315, # 6 p. 1057 - 1066

~%

1227-61-8 structure

1227-61-8

Literature: Journal fuer Praktische Chemie (Leipzig), , vol. 315, # 6 p. 1057 - 1066

~%

1227-61-8 structure

1227-61-8

Literature: Journal fuer Praktische Chemie (Leipzig), , vol. 315, # 6 p. 1057 - 1066

~%

1227-61-8 structure

1227-61-8

Literature: Chimica Therapeutica, , vol. 1, p. 82 - 86
HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%