Shanghai Nianxing Industrial Co., Ltd
China
Product Name: PEG2-Cl
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: PEG2-Cl
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

78925-46-9

78925-46-9 structure

78925-46-9 structure

Name: PEG2-Cl
Chemical Name: 3-(2-Chloroethoxy)-1-propanol
CAS Number: 78925-46-9
Molecular Formula: C₅H₁₁ClO₂
Molecular Weight: 138.593
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-11-24 08:17:00
Modify Date: 2024-01-08 12:46:10
PEG2-Cl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	3-(2-Chloroethoxy)-1-propanol
Synonyms	1-Propanol, 3-(2-chloroethoxy)- 3-(2-Chloroethoxy)-1-propanol 3-(2-chloroethoxy)propan-1-ol

Description	PEG2-Cl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density	1.1±0.1 g/cm3
Boiling Point	236.9±15.0 °C at 760 mmHg
Molecular Formula	C₅H₁₁ClO₂
Molecular Weight	138.593
Flash Point	97.1±20.4 °C
Exact Mass	138.044754
PSA	29.46000
LogP	0.26
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.441

5695-72-7 structure

5695-72-7

~%

78925-46-9 structure

78925-46-9

504-63-2 structure

504-63-2

Literature: Bonner, Trevor G.; Lewis, David; Rutter, Keith Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 1807 - 1810

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