78925-46-9
78925-46-9 structure
- Name: PEG2-Cl
- Chemical Name: 3-(2-Chloroethoxy)-1-propanol
- CAS Number: 78925-46-9
- Molecular Formula: C5H11ClO2
- Molecular Weight: 138.593
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-11-24 08:17:00
- Modify Date: 2024-01-08 12:46:10
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PEG2-Cl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 3-(2-Chloroethoxy)-1-propanol |
|---|---|
| Synonyms |
1-Propanol, 3-(2-chloroethoxy)-
3-(2-Chloroethoxy)-1-propanol 3-(2-chloroethoxy)propan-1-ol |
| Description | PEG2-Cl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 236.9±15.0 °C at 760 mmHg |
| Molecular Formula | C5H11ClO2 |
| Molecular Weight | 138.593 |
| Flash Point | 97.1±20.4 °C |
| Exact Mass | 138.044754 |
| PSA | 29.46000 |
| LogP | 0.26 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.441 |
