162666-34-4

162666-34-4 structure

Name: flutimide
Chemical Name: (5Z)-1-hydroxy-3-(2-methylpropyl)-5-(2-methylpropylidene)pyrazine-2,6-dione
CAS Number: 162666-34-4
Molecular Formula: C₁₂H₁₈N₂O₃
Molecular Weight: 238.28300
Catalog: Signaling Pathways Anti-infection Influenza Virus
Create Date: 2016-12-09 14:45:54
Modify Date: 2024-01-08 20:09:53
Flutimide is a novel endonuclease inhibitor of influenza virus. Flutimide selectively inhibits endonuclease with an IC50 value of 3 μM. Flutimide shows antiviral activity in cell culture. Flutimide can be used for the research of acute contagious respiratory disease, such as influenza[1].

Name	(5Z)-1-hydroxy-3-(2-methylpropyl)-5-(2-methylpropylidene)pyrazine-2,6-dione
Synonyms	Flutimide (3Z)-1-Hydroxy-5-isobutyl-3-(2-methylpropylidene)pyrazine-2,6(1H,3H)-dione 2,6-(1H,3H)-Pyrazinedione,1-hydroxy-5-(2-methylpropyl)-3-(2-methylpropylidene)-,(3Z)

Description	Flutimide is a novel endonuclease inhibitor of influenza virus. Flutimide selectively inhibits endonuclease with an IC50 value of 3 μM. Flutimide shows antiviral activity in cell culture. Flutimide can be used for the research of acute contagious respiratory disease, such as influenza[1].
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection
In Vitro	Flutimide inhibits the cap-dependent endonuclease of influenza virus with an IC50 value of 3 μM[1].
References	[1]. Otto D. Hensens, et al. Isolation and structure of flutimide, a novel endonuclease inhibitor of influenza virus. (1995) 36(12), 2005–2008.