Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Perillartine
Price: ￥118.0/20mg ￥138.0/1g ￥398.0/5g
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Perillartine
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Perillartine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

30950-27-7

30950-27-7 structure

30950-27-7 structure

Name: Perillartine
Chemical Name: Perillartine
CAS Number: 30950-27-7
Molecular Formula: C₁₀H₁₅NO
Molecular Weight: 165.232
Catalog: Biochemical Biochemical reagent Biological dye
Create Date: 2018-03-14 08:00:00
Modify Date: 2024-01-03 09:32:47
Perillartine is a sweetener, which activates the taste receptor type 1 member 2 (Tas1r2) subunit in a species-dependent manner.

Name	Perillartine
Synonyms	4-Isopropenyl-1-cyclohexene-1-carbaldehyde oxime 1-Cyclohexene-1-carboxaldehyde, 4- (1-methylethenyl)-, oxime Perillartin 1-perillaldehydealpha-antioxime 4-isopropenylcyclohex-1-enecarbaldehyde oxime l-perillaldehydealpha-syn-oxime 1-Cyclohexene-1-carboxaldehyde, 4-isopropenyl-, oxime (E)-N-Hydroxy-1-[4-(prop-1-en-2-yl)cyclohex-1-en-1-yl]methanimine 1-Cyclohexene-1-carboxaldehyde, 4-isopropenyl-, oxime (8CI) UNII:46S302515I 1-PERILLALDEHYDE A-ANTIOXIME 4-(1-Methylethenyl)-1-cyclohexene-1-carboxaldehyde Oxime Perillartine 1-Cyclohexene-1-carboxaldehyde, 4-(1-methylethenyl)-, oxime Perilla sugar Peryllartine (E)-N-Hydroxy-1-(4-isopropenyl-1-cyclohexen-1-yl)methanimine

Description	Perillartine is a sweetener, which activates the taste receptor type 1 member 2 (Tas1r2) subunit in a species-dependent manner.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Others
Target	TAS1R2[1]
In Vitro	The responses of the monomeric Tas1r2 subunits of human, rhesus monkey, squirrel monkey and mouse to Perillartine are examined, respectively. The human, rhesus monkey and squirrel monkey Tas1r2 subunits can be activated by Perillartine, while mouse Tas1r2 can not. The insensitivity of human, rhesus monkey, squirrel monkey and mouse Tas1r2 subunits to cyclamate precludes the probable involvement of Tas1r3 subunit in the assay. Replacement of the mouse Tas1r2 with rhesus monkey Tas1r2 (rhTas1r2/mTas1r3) leads to a gain of response to Perillartine. The dose-response curve show the efficacy of responses of the Tas1r2 subunits among species: hTAS1R2>rhTas1r2>smTas1r2>mTas1r2. These results demonstrate that the monomeric Tas1r2 subunit can be activated by Perillartine in a species-dependent manner[1].
References	[1]. Cai C, et al. Characterization of the Sweet Taste Receptor Tas1r2 from an Old World Monkey Species Rhesus Monkey and Species-Dependent Activation of the Monomeric Receptor by an Intense SweetenerPerillartine. PLoS One. 2016 Aug 1;11(8):e0160079.

Density	1.0±0.1 g/cm3
Boiling Point	271.4±40.0 °C at 760 mmHg
Melting Point	102°C
Molecular Formula	C₁₀H₁₅NO
Molecular Weight	165.232
Flash Point	158.3±16.6 °C
Exact Mass	165.115356
PSA	32.59000
LogP	3.33
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.513

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GW2975000

CHEMICAL NAME :: 1-Cyclohexene-1-carboxaldehyde, 4-isopropenyl-, anti-oxime

CAS REGISTRY NUMBER :: 30950-27-7

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C10-H15-N-O

MOLECULAR WEIGHT :: 165.26

WISWESSER LINE NOTATION :: L6UTJ A1UNQ DY1&U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AFDOAQ Quarterly Bulletin--Association of Food and Drug Officials of the United States. (Denver, CO) V.3-38, 1939-74. Volume(issue)/page/year: 15,82,1951 *** REVIEWS *** TOXICOLOGY REVIEW IDJOAS International Dental Journal. (A. Sijthoff, 37 Wagenstr, The Hague, Netherlands) V.1- 1950- Volume(issue)/page/year: 23,328,1973

Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	26-36/37/39