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250249-75-3

250249-75-3 structure
250249-75-3 structure
  • Name: Rutoside Trihydrate
  • Chemical Name: Rutin trihydrate
  • CAS Number: 250249-75-3
  • Molecular Formula: C20H36O3
  • Molecular Weight: 324.49800
  • Catalog: analytical chemistry Analytical reagent Ion chromatography reagent
  • Create Date: 2018-02-23 08:00:00
  • Modify Date: 2025-08-21 08:43:34
  • Rutin (Rutoside) trihydrate is a multifunctional natural flavonoid glycoside. Rutin trihydrate has been demonstrating excellent antioxidant, anti-inflammatory, anti-diabetic, and anti-carcinogenic properties. Cardioprotective and neuroprotective activities [1][2][3].
Name Rutin trihydrate
Synonyms Rutoside trihydrate
MFCD00149490
EINECS 205-814-1
Quercetin-3-rutinoside trihydrate,Vitamin P trihydrate
Description Rutin (Rutoside) trihydrate is a multifunctional natural flavonoid glycoside. Rutin trihydrate has been demonstrating excellent antioxidant, anti-inflammatory, anti-diabetic, and anti-carcinogenic properties. Cardioprotective and neuroprotective activities [1][2][3].
Related Catalog
In Vitro Rutin (Rutoside) trihydrate (0.5- 160 μM/ml; PC12 cells) decreases the acrylamide (ACR)-induced (5.46 mM) cytotoxicity significantly. ACR (5.46 mM) decreases cell viability in PC12 cells and pretreatment with rutin (0.5, 1, 1.5, 2.5, 5, 10, 20 and 40 μM/ml) increases the cell viability[2]. Due to the ability of Rutin and/or its metabolites to cross the blood brain barrier, it has also been shown to modify the cognitive and various behavioral symptoms of neurodegenerative diseases[3].
In Vivo Pretreatment of Rutin (100 and 200 mg/kg/day; i.p.) for long-term caused behavioural and neurochemical changes in aged WAG male rats[2].
References

[1]. Mel MMRD, et al. Formulation of microencapsulated rutin and evaluation of bioactivity and stability upon in vitro digestive and dialysis conditions. Int J Biol Macromol. 2020;159:316-323.

[2]. Doostkam A, et al. Effect of Rutin on Diabetic Auditory Neuropathy in an Experimental Rat Model. Clin Exp Otorhinolaryngol. 2021;14(3):259-267.

[3]. Habtemariam S. Rutin as a Natural Therapy for Alzheimer's Disease: Insights into its Mechanisms of Action. Curr Med Chem. 2016;23(9):860-873.
Density 1.82g/cm3
Boiling Point 983.1ºC at 760mmHg
Melting Point 195ºC
Molecular Formula C20H36O3
Molecular Weight 324.49800
Flash Point 325.4ºC
Exact Mass 324.26600
PSA 27.69000
LogP 6.34500
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.764
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Precautionary Statements P301 + P312 + P330
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases 22
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
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