284040-76-2

284040-76-2 structure

Name: Ac9-25 TFA
Chemical Name: Ac9-25
CAS Number: 284040-76-2
Molecular Formula: C₉₉H₁₄₃N₂₃O₃₃
Molecular Weight: 320.38700
Catalog: Research Areas Inflammation/Immunology
Create Date: 2017-08-25 11:35:33
Modify Date: 2024-04-05 17:32:12
Ac9-25, a N-terminal peptide of Annexin I, acts as a formyl peptide receptor (FPR) agonist and activates the neutrophil NADPH oxidase through FPR[1][2].

Name	Ac9-25
Synonyms	DR 4485 hydrochloride

Description	Ac9-25, a N-terminal peptide of Annexin I, acts as a formyl peptide receptor (FPR) agonist and activates the neutrophil NADPH oxidase through FPR[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Walther A, et al. A novel ligand of the formyl peptide receptor: annexin I regulates neutrophil extravasation by interacting with the FPR. Mol Cell. 2000;5(5):831-840. [2]. Karlsson J, et al. Neutrophil NADPH-oxidase activation by an annexin AI peptide is transduced by the formyl peptide receptor (FPR), whereas an inhibitory signal is generated independently of the FPR family receptors. J Leukoc Biol. 2005;78(3):762-771.