944401-58-5

944401-58-5 structure

Name: 2-amino-4-trifluoropyrimidine-5-boronic acid pinacol ester
Chemical Name: 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyrimidin-2-amine
CAS Number: 944401-58-5
Molecular Formula: C₁₁H₁₅BF₃N₃O₂
Molecular Weight: 289.062
Catalog: Pharmaceutical intermediate Heterocyclic compound Pyrimidine compound Fluoropyrimidine
Create Date: 2018-12-21 08:20:57
Modify Date: 2024-01-19 14:03:55

Name	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyrimidin-2-amine
Synonyms	2-Pyrimidinamine, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)- 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyrimidin-2-amine 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)-2-pyrimidinamine

Density	1.3±0.1 g/cm3
Boiling Point	403.8±55.0 °C at 760 mmHg
Molecular Formula	C₁₁H₁₅BF₃N₃O₂
Molecular Weight	289.062
Flash Point	198.0±31.5 °C
Exact Mass	289.120941
PSA	70.26000
LogP	1.95800
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.476
Storage condition	2-8°C

Hazard Codes	Xi
HS Code	2934999090

935534-47-7

73183-34-3

944401-58-5

16075-42-6

Literature: WO2008/98058 A1, ; Page/Page column 63-64 ; WO 2008/098058 A1

935534-47-7

73183-34-3

~40%

944401-58-5

Literature: NOVARTIS AG; Fairhurst, Robin Alec; Furet, Pascal; Kalthoff, Frank Stephan; Lerchner, Andreas; Rueeger, Heinrich Patent: US2014/135330 A1, 2014 ; Location in patent: Paragraph 0218 ;

16075-42-6

944401-58-5

Literature: US2013/225574 A1, ;

Precursor 3
935534-47-7 73183-34-3 16075-42-6
DownStream 0

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

56-41-7	108-65-6
56-35-9	64-17-5
67-56-1	108-88-3
141-78-6	1310-73-2
13463-67-7	1333-86-4