50611-86-4

50611-86-4 structure

Name: Coelenteramide
Chemical Name: oxidized Oplophorus luciferin
CAS Number: 50611-86-4
Molecular Formula: C₂₅H₂₁N₃O₃
Molecular Weight: 411.45300
Catalog: Research Areas Others
Create Date: 2017-10-12 14:38:57
Modify Date: 2024-01-08 12:52:54
Coelenteramide is a oxidative product of Coelenterazine (HY-18743). Coelenteramide can form a complex with apoAequorin/Ca2+, which is known as blue fluorescent protein (BFP) and shows continuous weak luminescence with Coelenterazine like a luciferase. Coelenteramide can be used as an imaging agent[1].

Name	oxidized Oplophorus luciferin
Synonyms	N-[2-benzyl-6-(4-oxocyclohexa-2,5-dien-1-ylidene)-1H-pyrazin-3-yl]-2-(4-hydroxyphenyl)acetamide COELENTERAMIDE CEI 2psj Oxidized Oplophorus luciferin

Description	Coelenteramide is a oxidative product of Coelenterazine (HY-18743). Coelenteramide can form a complex with apoAequorin/Ca2+, which is known as blue fluorescent protein (BFP) and shows continuous weak luminescence with Coelenterazine like a luciferase. Coelenteramide can be used as an imaging agent[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Inouye S, Nakamura M, Hosoya T. Formation of Coelenteramine from 2-Peroxycoelenterazine in the Ca2+ -Binding Photoprotein Aequorin. Photochem Photobiol. 2021 Dec 31.

Molecular Formula	C₂₅H₂₁N₃O₃
Molecular Weight	411.45300
Exact Mass	411.15800
PSA	98.57000
LogP	3.66370

1186119-92-5

~17%

50611-86-4

Literature: JNC Corporation Patent: US8026363 B2, 2011 ; Location in patent: Page/Page column 46-47 ;

55779-48-1

50611-86-4

Literature: Qi, Chen Feng; Gomi, Yasushiro; Hirano, Takashi; Ohashi, Mamoru; Ohmiya, Yoshihiro; Tsuji, Frederick I. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 13 p. 1607 - 1612

Precursor 2
1186119-92-5 55779-48-1
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