Coelenteramide

Modify Date: 2024-01-08 12:52:54

Coelenteramide Structure
Coelenteramide structure
Common Name Coelenteramide
CAS Number 50611-86-4 Molecular Weight 411.45300
Density N/A Boiling Point N/A
Molecular Formula C25H21N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Coelenteramide


Coelenteramide is a oxidative product of Coelenterazine (HY-18743). Coelenteramide can form a complex with apoAequorin/Ca2+, which is known as blue fluorescent protein (BFP) and shows continuous weak luminescence with Coelenterazine like a luciferase. Coelenteramide can be used as an imaging agent[1].

 Names

Name oxidized Oplophorus luciferin
Synonym More Synonyms

 Coelenteramide Biological Activity

Description Coelenteramide is a oxidative product of Coelenterazine (HY-18743). Coelenteramide can form a complex with apoAequorin/Ca2+, which is known as blue fluorescent protein (BFP) and shows continuous weak luminescence with Coelenterazine like a luciferase. Coelenteramide can be used as an imaging agent[1].
Related Catalog
References

[1]. Inouye S, Nakamura M, Hosoya T. Formation of Coelenteramine from 2-Peroxycoelenterazine in the Ca2+ -Binding Photoprotein Aequorin. Photochem Photobiol. 2021 Dec 31.

 Chemical & Physical Properties

Molecular Formula C25H21N3O3
Molecular Weight 411.45300
Exact Mass 411.15800
PSA 98.57000
LogP 3.66370

 Synthetic Route

~17%

Coelenteramide Structure

Coelenteramide

CAS#:50611-86-4

Literature: JNC Corporation Patent: US8026363 B2, 2011 ; Location in patent: Page/Page column 46-47 ;

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Coelenteramide Structure

Coelenteramide

CAS#:50611-86-4

Literature: Qi, Chen Feng; Gomi, Yasushiro; Hirano, Takashi; Ohashi, Mamoru; Ohmiya, Yoshihiro; Tsuji, Frederick I. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 13 p. 1607 - 1612

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

N-[2-benzyl-6-(4-oxocyclohexa-2,5-dien-1-ylidene)-1H-pyrazin-3-yl]-2-(4-hydroxyphenyl)acetamide
COELENTERAMIDE
CEI
2psj
Oxidized Oplophorus luciferin