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912849-73-1

912849-73-1 structure
912849-73-1 structure
  • Name: Azido-PEG10-amine
  • Chemical Name: 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
  • CAS Number: 912849-73-1
  • Molecular Formula: C22H46N4O10
  • Molecular Weight: 526.62100
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-12-30 18:41:20
  • Modify Date: 2024-01-05 23:39:00
  • Azido-PEG10-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
Synonyms O-(2-Aminoethyl)-O'-(2-azidoethyl)nonaethylene glycol
Azido-PEG-amine (n=10)
32-Azido-3,6,9,12,15,18,21,24,27,30-decaoxadotriacontan-1-amine
O-(2-Aminoethyl)-O inverted exclamation marka-(2-azidoethyl)nonaethylene glycol
Azido-PEG10-amine
Description Azido-PEG10-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C22H46N4O10
Molecular Weight 526.62100
Exact Mass 526.32100
PSA 168.07000
LogP 0.57446
Storage condition 2-8°C
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases 26
RIDADR NONH for all modes of transport
WGK Germany 3