60221-37-6
60221-37-6 structure
- Name: THP-PEG3-OH
- Chemical Name: 2-[2-[2-(oxan-2-yloxy)ethoxy]ethoxy]ethanol
- CAS Number: 60221-37-6
- Molecular Formula: C11H22O5
- Molecular Weight: 234.28900
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2017-11-11 03:06:06
- Modify Date: 2024-01-02 13:03:57
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THP-PEG3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2-[2-[2-(oxan-2-yloxy)ethoxy]ethoxy]ethanol |
|---|---|
| Synonyms |
2-{2-[2-(tetrahydro-2H-pyran-2-yloxy)ethoxy]ethoxy}ethanol
8-(2H-tetrahydropyran-2-yloxy)-3n36-dioxaoctan-1-ol 8-(1H-tetrahydropyran-2-yloxy)-3n63-dioxaoctan-1-ol Ethanol,2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy] |
| Description | THP-PEG3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C11H22O5 |
|---|---|
| Molecular Weight | 234.28900 |
| Exact Mass | 234.14700 |
| PSA | 57.15000 |
| LogP | 0.55510 |
