1189709-96-3

1189709-96-3 structure

Name: 5-Aminosalicylic acid-13C6
Chemical Name: 5-amino-2-hydroxybenzoic acid
CAS Number: 1189709-96-3
Molecular Formula: C₇H₇NO₃
Molecular Weight: 159.09100
Catalog: Signaling Pathways Cell Cycle/DNA Damage PAK
Create Date: 2017-08-09 00:55:07
Modify Date: 2026-07-27 20:00:47
5-Aminosalicylic acid-13C6 is the 13C labeled 5-Aminosalicylic Acid[1]. 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB[2][3][4].

Name	5-amino-2-hydroxybenzoic acid
Synonyms	Mesalazine/ Mesalamine Fisalamine-13C6 Mesalamine 13C6Q: What is Mesalamine 13C6 Q: What is the CAS Number of Mesalamine 13C6 Q: What is the storage condition of Mesalamine 13C6 Q: What e the applications of Mesalamine 13C6 5-Amino-2-hydroxybenzoic Acid-13C6 5-ASA-13C6 Asacolitin-13C6 Mesalamine-13C6 Pentasa-13C6 Mesalazine-13C6 Asacol-13C6 Claversal-13C6 5-Aminosalicylic Acid-13C6 Mesasal-13C6

Description	5-Aminosalicylic acid-13C6 is the 13C labeled 5-Aminosalicylic Acid[1]. 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB[2][3][4].
Related Catalog	Signaling Pathways >> Cytoskeleton >> PAK Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR Signaling Pathways >> Cell Cycle/DNA Damage >> PAK
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Dammann K, et al. PAK1 modulates a PPARγ/NF-κB cascade in intestinal inflammation. Biochim Biophys Acta. 2015 Oct;1853(10 Pt A):2349-60. [3]. Fang HM, et al. 5-aminosalicylic acid in combination with Nimesulide inhibits proliferation of colon carcinoma cells in vitro. World J Gastroenterol. 2007 May 2813(20):2872-7. [4]. Rousseaux C, et al. The 5-aminosalicylic acid antineoplastic effect in the intestine is mediated by PPARγ. Carcinogenesis. 2013 Nov34(11):2580-6.