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874208-94-3

874208-94-3 structure
874208-94-3 structure
  • Name: m-PEG5-NHS ester
  • Chemical Name: 3-(2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-propionic acid 2.5-dioxo-pyrrolidin-1-yl ester
  • CAS Number: 874208-94-3
  • Molecular Formula: C16H27NO9
  • Molecular Weight: 377.38700
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2016-08-30 19:55:18
  • Modify Date: 2025-08-26 19:03:00
  • m-PEG5-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Name 3-(2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-propionic acid 2.5-dioxo-pyrrolidin-1-yl ester
Synonyms m-peg5-nhs ester
Description m-PEG5-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.

Molecular Formula C16H27NO9
Molecular Weight 377.38700
Exact Mass 377.16900
PSA 109.83000
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