m-PEG5-NHS ester

Modify Date: 2024-01-07 10:16:27

m-PEG5-NHS ester Structure
m-PEG5-NHS ester structure
Common Name m-PEG5-NHS ester
CAS Number 874208-94-3 Molecular Weight 377.38700
Density N/A Boiling Point N/A
Molecular Formula C16H27NO9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG5-NHS ester


m-PEG5-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

 Names

Name 3-(2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-propionic acid 2.5-dioxo-pyrrolidin-1-yl ester
Synonym More Synonyms

 m-PEG5-NHS ester Biological Activity

Description m-PEG5-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.

 Chemical & Physical Properties

Molecular Formula C16H27NO9
Molecular Weight 377.38700
Exact Mass 377.16900
PSA 109.83000

 Synonyms

m-peg5-nhs ester
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