177980-10-8

177980-10-8 structure

Name: 2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine
Chemical Name: 2'-azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine
CAS Number: 177980-10-8
Molecular Formula: C₃₀H₂₉N₅O₇
Molecular Weight: 571.58
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2017-03-28 08:21:32
Modify Date: 2025-08-26 15:22:03
2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2'-azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine
Synonyms	2'-azido-5'-O-dimethoxytrityl-2'-deoxyuridine 2'-azido-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine 5'-O-(4,4'-dimethoxytrityl)-2'-azido-2'-deoxyuridine 2’-azido-2’-deoxyuridine 5'-O-dimethoxytrityl-2'-azido-2'-deoxyuridine

Description	2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.