2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine

Modify Date: 2024-01-13 15:37:22

2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine Structure
2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine structure
Common Name 2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine
CAS Number 177980-10-8 Molecular Weight 571.58
Density N/A Boiling Point N/A
Molecular Formula C30H29N5O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine


2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2'-azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine
Synonym More Synonyms

  Biological Activity

Description 2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C30H29N5O7
Molecular Weight 571.58
Exact Mass 571.20700
PSA 161.76000
LogP 2.95246

 Synonyms

2'-azido-5'-O-dimethoxytrityl-2'-deoxyuridine
2'-azido-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine
5'-O-(4,4'-dimethoxytrityl)-2'-azido-2'-deoxyuridine
2’-azido-2’-deoxyuridine
5'-O-dimethoxytrityl-2'-azido-2'-deoxyuridine