Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Adefovir dipivoxil
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Purity: 98.0%
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Contact: Ms Wang
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: Atomoxetine Hydrochloride
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Purity: 99.0%
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Contact: Anson
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142340-99-6

142340-99-6 structure

Name: Adefovir Dipivoxil
Chemical Name: Adefovir dipivoxil
CAS Number: 142340-99-6
Molecular Formula: C₂₀H₃₂N₅O₈P
Molecular Weight: 501.470
Catalog: API Synthetic anti-infective drugs Antiviral drugs
Create Date: 2018-02-07 08:00:00
Modify Date: 2026-06-30 10:43:04
Adefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body.Target: NRTIs; HBVAdefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. Adefovir Dipivoxil is used for treatment of hepatitis B and herpes simplex virus infection [1-3]. Adefovir Dipivoxil is approved for the treatment of chronic hepatitis B in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (primarily ALT) or histologically active disease. Adefovir Dipivoxil is a failed treatment for HIV[3, 4].

Name	Adefovir dipivoxil
Synonyms	Adefovir Impurity 3 9-[2-[Bis(pivaloyloxymethoxy)phosphorylmethoxy]ethyl]adenine ADEFOVIR Ade Vove Adefovir dipivoxil 100 μg/mL in Acetonitrile ADEFOVIR PIVOXIL AdefovirDipivoxlMin Adefovir dipivoxil ADV 9-(2[bis(Pivaloyloxymethoxy)phosphorylmethoxy]ethyl)adenine Adefovir dipivoxil, >= Bis(Pivaloyloxymethyl)-9-[(R)-2-(Phosphonomethoxy)Ethyl]Adenine Hepsera Adefovir Dipivoxil (bis-POM PMEA), nucleotide analog reverse transcriptase inhibitor ADEFOVIR DIPVOXIL Adefovir DipivoxilQ: What is Adefovir Dipivoxil Q: What is the CAS Number of Adefovir Dipivoxil Q: What is the storage condition of Adefovir Dipivoxil Q: What e the applications of Adefovir Dipivoxil Preveon MFCD00869897 ADEFOVIR DIPIVOXIL ((((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)-bis(oxy))bis(methylene) bis(2,2-dimethy ADEFOVIR DIPIVOLIX Adefovir dipivoxil //BP Adefovir Dipivoxyl BIS(PIVALOYLOXYMETHYL)-9-[2-(PHOSPHONOMETHOXY)ETHYL]ADENINE Di(pivaloyloxymethyl) ester Adefovir Dipivoxil > Adefovir Dipivoxi Hsera\|\|\|GS 0840\|\|\|Preveon Adefovir Dipivoxl 1,1'-[[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]phosphinylidene]bis(oxymethylene)]-2,2-dimethyl-propanoic acid ester Hsera BIS POM PMEA Adefovir dipivoxil,9-(2[bis(Pivaloyloxymethoxy)phosphorylmethoxy]ethyl)adenine 2,2-DiMethyl-propanoic Acid 1,1'-[[[[2-(6-Amino-9H-purin-9-yl)ethoxy]Methyl]phosphinylidene]bis(oxyMethylene)] Ester adefuweizhi GS 0840 Adefovir Dipivoxil API EINECS 200-001-8 Adefovir dipivoxil - Bio-X Propanoic acid, 2,2-dimethyl-, 1,1'-[[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]phosphinylidene]bis(oxymethylene)] ester ((((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate) Adefovir dipivoxil, 10 mM in DMSO BIS-POM PMEA; PREVEON; HSERA 9-[2-[bis[(pivaloyloxy)methoxy]phosphinyl]methoxy]ethyl]adenine Adefovir Dipivoxil Tablets Adefovir Dipivoxil(Preveon, Hsera) 3-{[2-(6-amino-9H-purin-9-yl)ethoxy]methyl}-8,8-dimethyl-3-oxido-7-oxo-2,4,6-trioxa-3-phosphanon-1-yl pivalate (non-preferred

Description	Adefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body.Target: NRTIs; HBVAdefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. Adefovir Dipivoxil is used for treatment of hepatitis B and herpes simplex virus infection [1-3]. Adefovir Dipivoxil is approved for the treatment of chronic hepatitis B in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (primarily ALT) or histologically active disease. Adefovir Dipivoxil is a failed treatment for HIV[3, 4].
Related Catalog	Signaling Pathways >> Anti-infection >> HBV Signaling Pathways >> Anti-infection >> Reverse Transcriptase Research Areas >> Infection
References	[1]. Marcellin, P., et al., Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B. N Engl J Med, 2003. 348(9): p. 808-16. [2]. Manolakopoulos, S., et al., Long-term therapy with adefovir dipivoxil in hepatitis B e antigen-negative patients developing resistance to lamivudine. Aliment Pharmacol Ther, 2008. 27(3): p. 266-73. [3]. Committee, A.I.S., A randomized placebo-controlled trial of adefovir dipivoxil in advanced HIV infection: the ADHOC trial. HIV Med, 2002. 3(4): p. 229-38. [4]. Fisher, E.J., et al., The safety and efficacy of adefovir dipivoxil in patients with advanced HIV disease: a randomized, placebo-controlled trial. AIDS, 2001. 15(13): p. 1695-700.

Density	1.4±0.1 g/cm3
Boiling Point	641.0±65.0 °C at 760 mmHg
Melting Point	98-102ºC
Molecular Formula	C₂₀H₃₂N₅O₈P
Molecular Weight	501.470
Flash Point	341.5±34.3 °C
Exact Mass	501.198853
PSA	176.79000
LogP	2.45
Vapour Pressure	0.0±1.9 mmHg at 25°C
Index of Refraction	1.569
Storage condition	−20°C

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H312-H332
Precautionary Statements	P280
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi
Risk Phrases	R20/21/22
Safety Phrases	36/37
RIDADR	NONH for all modes of transport