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882518-90-3

882518-90-3 structure
882518-90-3 structure
  • Name: Azido-PEG2-CH2COOH
  • Chemical Name: 2-(2-(2-azidoethoxy)ethoxy)acetic acid
  • CAS Number: 882518-90-3
  • Molecular Formula: C6H11N3O4
  • Molecular Weight: 189.16900
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-09-07 12:47:21
  • Modify Date: 2024-01-09 20:32:12
  • Azido-PEG2-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name 2-(2-(2-azidoethoxy)ethoxy)acetic acid
Synonyms 2-(2-azidoethoxy)ethoxyacetic acid
[2-(2-azide-ethoxy)ethoxy]acetate
3,6-dioxa-8-azidooctanoic acid
2-[2-(2-azidoethoxy)ethoxy]acetic acid
(2-(2-azidoethoxy)ethoxy)acetic acid
Description Azido-PEG2-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Yimin Qian, et al. Composés et procédés pour la dégradation ciblée de protéines contenant un bromodomaine. WO2017030814A1.

Molecular Formula C6H11N3O4
Molecular Weight 189.16900
Exact Mass 189.07500
PSA 105.51000
Storage condition 2-8°C
Precursor  0

DownStream  1