Azido-PEG2-CH2COOH

Modify Date: 2024-01-09 20:32:12

Azido-PEG2-CH2COOH Structure
Azido-PEG2-CH2COOH structure
Common Name Azido-PEG2-CH2COOH
CAS Number 882518-90-3 Molecular Weight 189.16900
Density N/A Boiling Point N/A
Molecular Formula C6H11N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG2-CH2COOH


Azido-PEG2-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name 2-(2-(2-azidoethoxy)ethoxy)acetic acid
Synonym More Synonyms

 Azido-PEG2-CH2COOH Biological Activity

Description Azido-PEG2-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Yimin Qian, et al. Composés et procédés pour la dégradation ciblée de protéines contenant un bromodomaine. WO2017030814A1.

 Chemical & Physical Properties

Molecular Formula C6H11N3O4
Molecular Weight 189.16900
Exact Mass 189.07500
PSA 105.51000
Storage condition 2-8°C

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

2-(2-azidoethoxy)ethoxyacetic acid
[2-(2-azide-ethoxy)ethoxy]acetate
3,6-dioxa-8-azidooctanoic acid
2-[2-(2-azidoethoxy)ethoxy]acetic acid
(2-(2-azidoethoxy)ethoxy)acetic acid
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