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942518-29-8

942518-29-8 structure
942518-29-8 structure
  • Name: L-Azidohomoalanine hydrochloride
  • Chemical Name: Butanoic acid, 2-amino-4-azido-, hydrochloride , (2S)
  • CAS Number: 942518-29-8
  • Molecular Formula: C4H9ClN4O2
  • Molecular Weight: 180.59300
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-07-13 22:52:26
  • Modify Date: 2024-01-16 11:04:54
  • L-Azidohomoalanine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Butanoic acid, 2-amino-4-azido-, hydrochloride , (2S)
Synonyms H-Dab(N3).HCl
26430 NGAMMA-AZIDO-L-2,4-DIAMINOBUTYRIC ACID
H-L-AHA-OH*HCL 4-AZIDO-L-HOMOALANINE, (S)-2-AMINO-4-AZIDOBUTANOIC ACID HYDROCHLORIDE
4-AZIDO-L-HOMOALANINE HYDROCHLORIDE
CLK-AA005-10 4-AZIDO-L-HOMOALANINE HCL, 10 MG PACK
4-Azido-L-homoalanine, (S)-2-Amino-4-azidobutanoic acid hydrochloride
Description L-Azidohomoalanine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C4H9ClN4O2
Molecular Weight 180.59300
Exact Mass 180.04100
PSA 113.07000
LogP 1.05376
HS Code 2929909090
HS Code 2929909090
Summary 2929909090 other compounds with other nitrogen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%