L-Azidohomoalanine hydrochloride

Modify Date: 2024-01-16 11:04:54

L-Azidohomoalanine hydrochloride Structure
L-Azidohomoalanine hydrochloride structure
Common Name L-Azidohomoalanine hydrochloride
CAS Number 942518-29-8 Molecular Weight 180.59300
Density N/A Boiling Point N/A
Molecular Formula C4H9ClN4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of L-Azidohomoalanine hydrochloride


L-Azidohomoalanine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Butanoic acid, 2-amino-4-azido-, hydrochloride , (2S)
Synonym More Synonyms

 L-Azidohomoalanine hydrochloride Biological Activity

Description L-Azidohomoalanine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C4H9ClN4O2
Molecular Weight 180.59300
Exact Mass 180.04100
PSA 113.07000
LogP 1.05376

 Safety Information

HS Code 2929909090

 Customs

HS Code 2929909090
Summary 2929909090 other compounds with other nitrogen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Synonyms

H-Dab(N3).HCl
26430 NGAMMA-AZIDO-L-2,4-DIAMINOBUTYRIC ACID
H-L-AHA-OH*HCL 4-AZIDO-L-HOMOALANINE, (S)-2-AMINO-4-AZIDOBUTANOIC ACID HYDROCHLORIDE
4-AZIDO-L-HOMOALANINE HYDROCHLORIDE
CLK-AA005-10 4-AZIDO-L-HOMOALANINE HCL, 10 MG PACK
4-Azido-L-homoalanine, (S)-2-Amino-4-azidobutanoic acid hydrochloride
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