946075-13-4

946075-13-4 structure

Name: isavuconazonium sulfate
Chemical Name: isavuconazonium sulfate
CAS Number: 946075-13-4
Molecular Formula: C₃₅H₃₆F₂N₈O₉S₂
Molecular Weight: 814.835
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2018-05-14 08:00:00
Modify Date: 2024-01-04 17:24:17
Isavuconazonium sulfate (BAL8557-002), the prodrug of the active triazole Isavuconazole, is an orally active antifungal agent. Isavuconazonium sulfate is used for invasive aspergillosis and mucormycosis[1][2].

Name	isavuconazonium sulfate
Synonyms	Cresemba Isavuconazonium sulfate (2-{[(1-{1-[(2R,3R)-3-[4-(4-Cyanophenyl)-1,3-thiazol-2-yl]-2-(2,5-difluorophenyl)-2-hydroxybutyl]-1H-1,2,4-triazol-4-ium-4-yl}ethoxy)carbonyl](methyl)amino}-3-pyridinyl)methyl N-methylglycinate hydrogen sulfate

Description	Isavuconazonium sulfate (BAL8557-002), the prodrug of the active triazole Isavuconazole, is an orally active antifungal agent. Isavuconazonium sulfate is used for invasive aspergillosis and mucormycosis[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Schmitt-Hoffmann AH, et al. Tissue Distribution and Elimination of Isavuconazole following Single and Repeat Oral-Dose Administration of Isavuconazonium Sulfate to Rats. Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e01292-17. [2]. Murrell D, et al. Isavuconazonium sulfate: a triazole prodrug for invasive fungal infections. Int J Pharm Pract. 2017 Feb;25(1):18-30.