isavuconazonium sulfate

Modify Date: 2025-08-27 12:35:01

isavuconazonium sulfate Structure
isavuconazonium sulfate structure
Common Name isavuconazonium sulfate
CAS Number 946075-13-4 Molecular Weight 814.835
Density N/A Boiling Point N/A
Molecular Formula C35H36F2N8O9S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of isavuconazonium sulfate


Isavuconazonium sulfate (BAL8557-002), the prodrug of the active triazole Isavuconazole, is an orally active antifungal agent. Isavuconazonium sulfate is used for invasive aspergillosis and mucormycosis[1][2].

 Names

Name isavuconazonium sulfate
Synonym More Synonyms

 isavuconazonium sulfate Biological Activity

Description Isavuconazonium sulfate (BAL8557-002), the prodrug of the active triazole Isavuconazole, is an orally active antifungal agent. Isavuconazonium sulfate is used for invasive aspergillosis and mucormycosis[1][2].
Related Catalog
References

[1]. Schmitt-Hoffmann AH, et al. Tissue Distribution and Elimination of Isavuconazole following Single and Repeat Oral-Dose Administration of Isavuconazonium Sulfate to Rats. Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e01292-17.

[2]. Murrell D, et al. Isavuconazonium sulfate: a triazole prodrug for invasive fungal infections. Int J Pharm Pract. 2017 Feb;25(1):18-30.

 Chemical & Physical Properties

Molecular Formula C35H36F2N8O9S2
Molecular Weight 814.835
Exact Mass 814.201477
PSA 273.42000
LogP 5.06088
Storage condition -20℃

 Synonyms

Cresemba
Isavuconazonium sulfate
(2-{[(1-{1-[(2R,3R)-3-[4-(4-Cyanophenyl)-1,3-thiazol-2-yl]-2-(2,5-difluorophenyl)-2-hydroxybutyl]-1H-1,2,4-triazol-4-ium-4-yl}ethoxy)carbonyl](methyl)amino}-3-pyridinyl)methyl N-methylglycinate hydrogen sulfate
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