Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Bisphenol A
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: bisphenol A
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson
Email: info@tianfuchem.com

80-05-7

80-05-7 structure

Name: bisphenol A
Chemical Name: bisphenol A
CAS Number: 80-05-7
Molecular Formula: C₁₅H₁₆O₂
Molecular Weight: 228.286
Catalog: Organic raw materials Alcohols, phenols, phenolic compounds and derivatives Phenol and its halogenated, sulfonated, nitrated or nitrosated derivatives
Create Date: 2018-02-07 08:00:00
Modify Date: 2026-07-12 17:09:29
Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[1][2][3].

Name	bisphenol A
Synonyms	2,2-Bis(4-hydroxyphenyl)propane 2,2-Bis(4-hydroxyphenyl)-propa Phenol, 4,4'-(1-methylethylidene)bis β-Di-p-hydroxyphenylpropane Bicifadinum 2,2-Bis(4,4'-hydroxyphenyl)propane ucbisphenola pluracol245 Diphenylolpropan Hidorin F 285 (2,2-BIS(PA-HYDROXYPHENYL)PROPANE propane,2,2-bis(4-hydroxyphenyl) 4,4’-bisphenola Phenol, (1-methylethylidene)bis Bicifadino 2,2-bis(4-hydroxyphenyl)-popane dimethylbis(p-hydroxyphenyl)methane ucbisphenolhp Pluracol 4,4'-(1-Methylethylidene)bisphenol Ipognox 88 DI-(PA-HYDROXYPHENYL)DIMETHYLMETHANE 2,2-bis-4’-hydroxyfenylpropan(czech) BISPHENOL A 2,2-Di-(4-hydroxyphenyl)propane Dian BPA Pabis A 4,4'-Methylethylidendbisphenol 2,2-Di(4-phenylol)propane 4,4’-dimethylmethylenedi-pheno 4,4'-Isopropylidenediphenol dimethylmethylene-p,p’-diphenol dimethyl bis(p-hydroxyphenyl)methane 2,2-di-(4'-Hydroxyphenyl)-propane 4,4'-propane-2,2-diyldiphenol b,b'-Bis(p-hydroxyphenyl)propane 2,2-bis-4’-hydroxyfenylpropan 4,4’-dihydroxydiphenyldimethylmethane 4,4’-(1-methylethylidene)bisphenol Rikabanol 4,4’-(1-methylethylidene)bis-pheno 4,4’-dihydroxydiphenyl-2,2-propane 2,2-bis(p-hydroxyphenyl)-propan 4,4'-(1-Methylethane-1,1-diyl)diphenol EINECS 201-245-8 Bisferol A bisferola(czech) 2,2-Di(4-hydroxyphenyl)propane 4,4′-isopropylidenediphenol Propane, 2,2-bis(p-hydroxyphenyl) 2,2-Bis-4'-hydroxyfenylpropan 4,4'-ISOPROPYLIDENEDIPHENOL, 500MG, NEAT Phenol, 4,4'-dimethylmethylenedi 2,2-Bis (4-hydroxyphenol) propane Dimethylmethylene-p,p'-diphenol 4,4’-(1-methylethylidene)bis-Phenol Parabis di-2,2-(4-Hydroxyphenyl)propane pabisa bisphenola(bpa) 2,2-Bis(hydroxyphenyl)propane bisferola Bis(p-hydroxyphenyl)propane Dimethyl bis(p-hydroxyphenyl)methane MFCD03427359 Diano 4,4’-dihydroxydiphenylpropane 4,4’-isopropylidenebisphenol bis-Phenolpropane Phenol, 4,4'-isopropylidenedi 4,4'-isopropyldidenediphenol 4,4’-dihydroxydiphenylisopropane 4,4'-(2,2-Propanediyl)diphenol

Description	Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[1][2][3].
Related Catalog	Research Areas >> Endocrinology
Target	Human Endogenous Metabolite
References	[1]. Huang M, et al. Bisphenol A and its analogues bisphenol S, bisphenol F and bisphenol AF induce oxidative stress and biomacromolecular damage in human granulosa KGN cells. Chemosphere. 2020 Apr 9;253:126707. [2]. Rubin BS, et al. Bisphenol A: an endocrine disruptor with widespread exposure and multiple effects. J Steroid Biochem Mol Biol. 2011 Oct;127(1-2):27-34.

Density	1.1±0.1 g/cm3
Boiling Point	400.8±25.0 °C at 760 mmHg
Melting Point	158-159 °C(lit.)
Molecular Formula	C₁₅H₁₆O₂
Molecular Weight	228.286
Flash Point	192.4±17.8 °C
Exact Mass	228.115036
PSA	40.46000
LogP	3.43
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.599
Storage condition	Refrigerator
Water Solubility	<0.1 g/100 mL at 21.5 ºC

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SL6300000

CHEMICAL NAME :: Phenol, 4,4'-isopropylidenedi-

CAS REGISTRY NUMBER :: 80-05-7

BEILSTEIN REFERENCE NO. :: 1107700

LAST UPDATED :: 199712

DATA ITEMS CITED :: 49

MOLECULAR FORMULA :: C15-H16-O2

MOLECULAR WEIGHT :: 228.31

WISWESSER LINE NOTATION :: QR DX1&1&R DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2400 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

TYPE OF TEST :: LC - Lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1700 mg/m3/2H

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Liver - fatty liver degeneration Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2230 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 3 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 4 gm/kg

TOXIC EFFECTS :: Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 6500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 12 mg/kg/12D-I

TOXIC EFFECTS :: Liver - fatty liver degeneration Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 42 gm/kg/8W-C

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5460 mg/kg/13W-C

TOXIC EFFECTS :: Gastrointestinal - other changes Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 31500 mg/kg/9W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - urine volume increased Liver - other changes Blood - other hemolysis with or without anemia

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 455 mg/kg/26W-I

TOXIC EFFECTS :: Behavioral - alteration of classical conditioning Liver - liver function tests impaired Blood - other changes

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 150 mg/m3/6H/13W-I

TOXIC EFFECTS :: Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 47 mg/m3/2H/19W-I

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - urine volume decreased Endocrine - changes in spleen weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 273 gm/kg/13W-C

TOXIC EFFECTS :: Liver - other changes Related to Chronic Data - death

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/m3/2H/41D-I

TOXIC EFFECTS :: Liver - fatty liver degeneration Kidney, Ureter, Bladder - other changes Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 31500 mg/kg/9W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes in urine composition Blood - changes in erythrocyte (RBC) count Biochemical - Metabolism (Intermediary) - lipids including transport

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 4550 mg/kg/26W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes in urine composition Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Endocrine - other changes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 10 gm/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 15 gm/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 1275 mg/kg

SEX/DURATION :: female 1-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 1275 mg/kg

SEX/DURATION :: female 1-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 1875 mg/kg

SEX/DURATION :: female 1-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 1275 mg/kg

SEX/DURATION :: female 1-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - Central Nervous System

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 1875 mg/kg

SEX/DURATION :: female 1-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - gastrointestinal system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 12500 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - fetal death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 7500 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 12500 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - uterus, cervix, vagina

TYPE OF TEST :: DNA adduct

TYPE OF TEST :: DNA adduct

MUTATION DATA

TYPE OF TEST :: Micronucleus test

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 200 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 390,21,1997 *** REVIEWS *** TOXICOLOGY REVIEW FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 13,747,1989 *** U.S. STANDARDS AND REGULATIONS *** OSHA PEL (Shipyard):CL 0.5 ppm (2.8 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 5 mg/m3 JAN 1993 OEL-THAILAND:TWA 0.5 ppm (2.8 mg/m3) JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 12845 No. of Facilities: 5427 (estimated) No. of Industries: 82 No. of Occupations: 74 No. of Employees: 71597 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T0995 No. of Facilities: 6 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 2180 (estimated) No. of Female Employees: 49 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 12845 No. of Facilities: 5987 (estimated) No. of Industries: 70 No. of Occupations: 78 No. of Employees: 92138 (estimated) No. of Female Employees: 15144 (estimated)

Symbol	GHS05, GHS07, GHS08, GHS09
Signal Word	Danger
Hazard Statements	H317-H318-H335-H361f-H411
Precautionary Statements	P261-P273-P280-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	Xn:Harmful
Risk Phrases	R37;R41;R43;R62
Safety Phrases	S26-S36/37/39-S45-S46-S39-S36/37
RIDADR	UN 3077 9 / PGIII
WGK Germany	2
RTECS	SL6300000
HS Code	2907230001

Precursor 10
67-64-1 108-95-2 5109-95-5 117-08-8
75-77-4 109-79-5 2720-53-8 13034-76-9
119923-02-3 123-54-6
DownStream 10
109348-07-4 1745-89-7 105577-85-3 59501-41-6
3739-67-1 4387-16-0 38103-06-9 3253-39-2
307-34-6 472-41-3

HS Code	2907230001
Summary	2907230001 4,4'-(propane-2,2-diyl)diphenol VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none Lowest tariff:5.5% General tariff:30.0%

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1421494-70-3	1421515-89-0
1421464-46-1	1421481-20-0
1421498-25-0	1396635-24-7
1243313-48-5	1448063-37-3
1448027-45-9	1448037-36-2