Name | alosetron hydrochloride |
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Synonyms |
Alosetron hydrochloride
5-méthyl-2-[(4-méthyl-1H-imidazol-5-yl)méthyl]-2,3,4,5-tétrahydro-1H-pyrido[4,3-b]indol-1-one chlorhydrate gr 68755c 1H-pyrido[4,3-b]indol-1-one, 2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-, monohydrochloride 1H-Pyrido[4,3-b]indol-1-one, 2,3,4,5-tetrahydro-5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-, hydrochloride (1:1) 1H-pyrido[4,3-b]indol-1-one, 2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-, hydrochloride (1:1) LOTRONEX MFCD03453647 Alosetron HCl GR-68755C 5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one hydrochloride 5-Methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one hydrochloride (1:1) 5-Methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-onhydrochlorid Alosetron (Hydrochloride) |
Description | Alosetron Hcl is a Serotonin 5HT3-receptor antagonist that is used in treatment of irritable bowel syndrome.IC50 Value: Target: 5-HT ReceptorAlosetron has an antagonist action on the 5-HT3 receptors of the enteric nervous system of the gastrointestinal tract. While being a 5-HT3 antagonist like ondansetron, it is not classified or approved as an antiemetic. Since stimulation of 5-HT3 receptors is positively correlated with gastrointestinal motility, alosetron's 5-HT3 antagonism slows the movement of fecal matter through the large intestine, increasing the extent to which water is absorbed, and decreasing the moisture and volume of the remaining waste products. From Wikipedia. |
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Related Catalog | |
References |
Density | 1.34g/cm3 |
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Boiling Point | 648.1ºC at 760 mmHg |
Melting Point | 288-291ºC |
Molecular Formula | C17H19ClN4O |
Molecular Weight | 330.812 |
Flash Point | 345.8ºC |
Exact Mass | 330.124725 |
PSA | 53.92000 |
LogP | 3.14820 |
Vapour Pressure | 1.1E-16mmHg at 25°C |
Storage condition | Refrigerator |
Symbol |
GHS06, GHS09 |
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Signal Word | Danger |
Hazard Statements | H301-H319-H411 |
Precautionary Statements | P273-P301 + P310-P305 + P351 + P338 |
Hazard Codes | T,Xi |
Risk Phrases | 25-36-52/53 |
Safety Phrases | 26-45 |
RIDADR | UN 2811 6.1 / PGIII |
HS Code | 2933990090 |
HS Code | 2933990090 |
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Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |